The interaction of RPTP-alpha and the SH2 domain of Fyn induces an interaction of Fyn Tyr531 with the D1 domain of RPTP-alpha. This induces dephosphorylation of Tyr531 and activates Fyn.
Leshchyns'ka, I, Morrow, JS, Sytnyk, V, Schachner, M
Leshchyns'ka, I, Bodrikov, V, Sytnyk, V, den Hertog, J, Schachner, M, Overvoorde, J
protein tyrosine phosphatase activity of Receptor-type tyrosine-protein phosphatase T [plasma membrane]
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