Reactome: A Curated Pathway Database

Phosphorylation of L1 by p90rsk

Stable Identifier
R-NUL-445066
Type
Reaction
Species
Homo sapiens
Compartment
Summation

p90rsk associates with the internalized L1 in the endosomes and phosphorylates it at Ser1152. This phosphorylation may regulate the interactions of L1 and intracellular signaling cascades or cytoskeletal elements involved in neurite outgrowth on specific substrates.

Literature References
Participants
This entity is regulated by:
Title Physical Entity Activity
protein serine/threonine kinase activity of p90rsk [cytosol] p90rsk [cytosol] protein serine/threonine kinase activity (0004674)
Orthologous Events