Phosphorylation of L1 by p90rsk

Stable Identifier
R-NUL-445066
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Phosphorylation of L1 by p90rsk
p90rsk associates with the internalized L1 in the endosomes and phosphorylates it at Ser1152. This phosphorylation may regulate the interactions of L1 and intracellular signaling cascades or cytoskeletal elements involved in neurite outgrowth on specific substrates.
Literature References
PubMed ID Title Journal Year
8663493 Involvement of p90rsk in neurite outgrowth mediated by the cell adhesion molecule L1

Landreth, G, Schaefer, AW, Lemmon, V, Wong, EV

J Biol Chem 1996
Participants
Input
Output
Catalyst Activity

protein serine/threonine kinase activity of Rps6ka1 [cytosol]

Physical Entity
Rps6ka1 [cytosol] (Rattus norvegicus)
Activity
protein serine/threonine kinase activity (GO:0004674)
Orthologous Events
Phosphorylation of L1 by p90rsk (Homo sapiens)
Authored
Garapati, P V  (2008-07-30)
Reviewed
Maness, PF  (2010-02-16)
Created
Garapati, P V  (2009-10-27)
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