Transport of L1 from C-domain to P-domain

Stable Identifier
R-NUL-445082
Type
Reaction [binding]
Species
Mus musculus
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Transport of L1 from C-domain to P-domain
Endocytosis is followed by the vesicular transport and recycling of L1 from central (C)-domain into the peripheral (P)-domain of growth cones.
Microtubules serve as a rail on which motor proteins convey L1 containing organelles. KIF4 is a plus end motor protein involved in the anterograde transport of L1 containing vesicles along microtubules.
Literature References
PubMed ID Title Journal Year
10804209 Recycling of the cell adhesion molecule L1 in axonal growth cones

Kamiguchi, H, Lemmon, V

J Neurosci 2000
10747093 Evidence for the involvement of KIF4 in the anterograde transport of L1-containing vesicles

Peretti, D, Caceres, A, Quiroga, S, Peris, L, Rosso, S

J Cell Biol 2000
Participants
Input
Output
Orthologous Events
Transport of L1 from C-domain to P-domain (Homo sapiens)
Authored
Garapati, P V  (2008-07-30)
Reviewed
Maness, PF  (2010-02-16)
Created
Garapati, P V  (2009-10-27)
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