NICD4 binds RBPJ and MAML in the nucleus

Stable Identifier
R-NUL-9013699
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
NICD4 binds RBPJ and MAML in the nucleus
Mouse Notch4 intracellular domain (NICD4) forms a complex with human RBPJ (CSL) and any of the human mastermind proteins MAML1, MAML2 or MAML3 (Lin et al. 2002).
Literature References
PubMed ID Title Journal Year
12386158 Identification of new human mastermind proteins defines a family that consists of positive regulators for notch signaling

Oyama, T, Nagase, T, Lin, SE, Kitagawa, M, Harigaya, K

J. Biol. Chem. 2002
Participants
Input
Output
Orthologous Events
NICD4 binds RBPJ and MAML in the nucleus (Homo sapiens)
Authored
Orlic-Milacic, M  (2018-04-05)
Reviewed
Haw, R  (2018-05-01)
Created
Orlic-Milacic, M  (2017-07-25)
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