Carboxypeptidase E (rat Carboxypeptidase H) cleaves Insulin(25-56) to yield Insulin(25-54)

Stable Identifier
R-NUL-9023166
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
General
SVG |   | PPTX  | SBGN
Carboxypeptidase E (rat Carboxypeptidase H) cleaves Insulin(25-56) to yield Insulin(25-54)
Carboxypeptidase E (also called Carboxypeptidase H) purified from rat beta cells cleaves the C-terminal two amino acid residues (ariginine-56 and arginine-55) from the B chain derived from human proinsulin (Davidson and Hutton 1987).
Literature References
Participants
Catalyst Activity

metallocarboxypeptidase activity of Cpe:Zn2+ [secretory granule membrane]

Orthologous Events
Authored
Reviewed
Created
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