Ntrk2 phosphorylates Frs2

Stable Identifier
R-NUL-9031971
Type
Reaction [transition]
Species
Homo sapiens
Compartment
plasma membrane, cytosol
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Ntrk2 phosphorylates Frs2
Recombinant rat Ntrk2 (TrkB), activated by recombinant human BDNF or NTF4, phosphorylates mouse Frs2 on unknown tyrosine residues (Yuen and Mobley 1999).
Literature References
PubMed ID Title Journal Year
10486198 Early BDNF, NT-3, and NT-4 signaling events

Yuen, EC, Mobley, WC

Exp. Neurol. 1999
Participants
Input
Output
Catalyst Activity

protein tyrosine kinase activity of BDNF,NTF4:p-5Y-Ntrk2:Frs2 [plasma membrane]

Physical Entity
BDNF,NTF4:p-5Y-Ntrk2:Frs2 [plasma membrane] (Homo sapiens)
Activity
protein tyrosine kinase activity (GO:0004713)
Orthologous Events
NTRK2 phosphorylates FRS2 (Homo sapiens)
Authored
Orlic-Milacic, M  (2018-01-05)
Reviewed
Castrén, E  (2018-02-13)
Antila, H  (2018-02-13)
Created
Orlic-Milacic, M  (2017-12-04)
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