Srebf1 gene expression is inhibited by FOXO1

Stable Identifier
R-NUL-9625366
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, endoplasmic reticulum membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Srebf1 gene expression is inhibited by FOXO1
Recombinant human FOXO1 inhibits transcription from the rat Srebf1 promoter-luciferase reporter construct (Deng et al. 2012).
Literature References
PubMed ID Title Journal Year
22511764 FoxO1 inhibits sterol regulatory element-binding protein-1c (SREBP-1c) gene expression via transcription factors Sp1 and SREBP-1c

Elam, MB, Williams, JB, O-Sullivan, I, Raghow, R, Unterman, TG, Dong, Q, Deng, X, Park, EA, Zhang, W

J. Biol. Chem. 2012
Participants
Input
Output
This event is regulated
Negatively by
Regulator
FOXO1 [nucleoplasm] (Homo sapiens)
Orthologous Events
SREBF1 gene expression is inhibited by FOXO1 (Homo sapiens)
Authored
Orlic-Milacic, M  (2018-10-23)
Reviewed
Donlon, T  (2018-10-23)
Created
Orlic-Milacic, M  (2018-10-19)
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