CREBBP acetylates Foxo1

Stable Identifier
R-NUL-9626944
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
CREBBP acetylates Foxo1
Recombinant human histone acetyltransferase CREBBP (CBP) acetylates recombinant mouse Foxo1 on conserved lysine residues K242, K245 and K262 (Daitoku et al. 2004).
Literature References
PubMed ID Title Journal Year
15220471 Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity

Matsuzaki, H, Ohshima, T, Daitoku, H, Aratani, S, Miyagishi, M, Fukamizu, A, Hatta, M, Nakajima, T

Proc. Natl. Acad. Sci. U.S.A. 2004
Participants
Input
Output
Catalyst Activity

histone acetyltransferase activity of Crebbp [nucleoplasm]

Physical Entity
Crebbp [nucleoplasm] (Mus musculus)
Activity
histone acetyltransferase activity (GO:0004402)
Orthologous Events
CREBBP acetylates FOXO1 (Homo sapiens)
Authored
Orlic-Milacic, M  (2018-10-31)
Reviewed
Bertaggia, E  (2018-10-26)
Created
Orlic-Milacic, M  (2018-10-30)
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