p-T-EIF2AK1 phosphorylates EIF2S1 (eIF2-alpha)

Stable Identifier
R-OCU-9655594
Type
Reaction [transition]
Species
Oryctolagus cuniculus
Compartment
cytosol
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
p-T-EIF2AK1 phosphorylates EIF2S1 (eIF2-alpha)
Phosphorylated EIF2AK1 phosphorylates EIF2S1 (eIF2-alpha) on serine-51 (Chefalo et al. 1998).
Literature References
PubMed ID Title Journal Year
9874252 Heme-regulated eIF-2alpha kinase purifies as a hemoprotein

Rafie-Kolpin, M, Chen, JJ, Oh, J, Kan, B, Chefalo, PJ

Eur. J. Biochem. 1998
Participants
Input
Output
Catalyst Activity

protein serine/threonine kinase activity of p-T-EIF2AK1 [cytosol]

Physical Entity
p-T-EIF2AK1 [cytosol] (Oryctolagus cuniculus)
Activity
protein serine/threonine kinase activity (GO:0004674)
Orthologous Events
p-T,T486,T488-EIF2AK1 phosphorylates EIF2S1 (eIF2-alpha) (Homo sapiens)
Authored
May, B  (2019-07-24)
Reviewed
Chen, JJ  (2019-10-22)
Created
May, B  (2019-07-24)
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