GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH

Stable Identifier
R-PFA-5694071
Type
Reaction [transition]
Species
Plasmodium falciparum
Compartment
Synonyms
GLO1 dimer:2xZn2+ trnasforms glutathione and methylglyoxal to lactoylglutathione
Locations in the PathwayBrowser
General
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This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
lactoylglutathione lyase activity of GLO1 dimer:2xZn2+ [cytosol]
Physical Entity
Activity
Inferred From
Created