BCKDH transfers CoA group from CoA-SH to BCAAs

Stable Identifier
R-PFA-70713
Type
Reaction [transition]
Species
Plasmodium falciparum
Compartment
Synonyms
a-ketoisocaproate, a-keto b-methylvalerate, or a-ketoisovalerate + CoA + NAD+ => isovaleryl-CoA, a-methylbutyryl-CoA, or isobuyryl-CoA + CO2 + NADH + H+, Oxidative decarboxylation of branched-chain alpha-keto acids
Locations in the PathwayBrowser
General
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This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Participants
Participates
Catalyst Activity

CoA-transferase activity of lipo-BCKDH [mitochondrial matrix]

Inferred From
Created
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