Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
RPS27A(77-156) [cytosol]
Stable Identifier
R-PFA-72363
Type
Protein [EntityWithAccessionedSequence]
Species
Plasmodium falciparum
Compartment
cytosol
Synonyms
Q8ID50
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Plasmodium falciparum)
Nonsense-Mediated Decay (NMD) (Plasmodium falciparum)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Plasmodium falciparum)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Plasmodium falciparum)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Plasmodium falciparum)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
40S ribosomal complex [cytosol] (Plasmodium falciparum)
RPS27A(77-156) [cytosol] (Plasmodium falciparum)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Plasmodium falciparum)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
40S ribosomal complex [cytosol] (Plasmodium falciparum)
RPS27A(77-156) [cytosol] (Plasmodium falciparum)
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Plasmodium falciparum)
Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Plasmodium falciparum)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
40S ribosomal complex [cytosol] (Plasmodium falciparum)
RPS27A(77-156) [cytosol] (Plasmodium falciparum)
UPF1:eRF3 Complex on Translated mRNA [cytosol] (Plasmodium falciparum)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
40S ribosomal complex [cytosol] (Plasmodium falciparum)
RPS27A(77-156) [cytosol] (Plasmodium falciparum)
Metabolism of proteins (Plasmodium falciparum)
Post-translational protein modification (Plasmodium falciparum)
Protein ubiquitination (Plasmodium falciparum)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Plasmodium falciparum)
UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin (Plasmodium falciparum)
RPS27A(77-156) [cytosol] (Plasmodium falciparum)
Translation (Plasmodium falciparum)
Eukaryotic Translation Initiation (Plasmodium falciparum)
Cap-dependent Translation Initiation (Plasmodium falciparum)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Plasmodium falciparum)
Translation initiation complex formation (Plasmodium falciparum)
Formation of translation initiation complexes containing mRNA that does not circularize (Plasmodium falciparum)
43S complex [cytosol] (Plasmodium falciparum)
40S ribosomal complex [cytosol] (Plasmodium falciparum)
RPS27A(77-156) [cytosol] (Plasmodium falciparum)
48S complex [cytosol] (Plasmodium falciparum)
43S complex [cytosol] (Plasmodium falciparum)
40S ribosomal complex [cytosol] (Plasmodium falciparum)
RPS27A(77-156) [cytosol] (Plasmodium falciparum)
Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation (Plasmodium falciparum)
43S complex [cytosol] (Plasmodium falciparum)
40S ribosomal complex [cytosol] (Plasmodium falciparum)
RPS27A(77-156) [cytosol] (Plasmodium falciparum)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Plasmodium falciparum)
43S complex [cytosol] (Plasmodium falciparum)
40S ribosomal complex [cytosol] (Plasmodium falciparum)
RPS27A(77-156) [cytosol] (Plasmodium falciparum)
Formation of a pool of free 40S subunits (Plasmodium falciparum)
Release of 40S and 60S subunits from the 80S ribosome (Plasmodium falciparum)
40S ribosomal complex [cytosol] (Plasmodium falciparum)
RPS27A(77-156) [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
40S ribosomal complex [cytosol] (Plasmodium falciparum)
RPS27A(77-156) [cytosol] (Plasmodium falciparum)
eIF3 and eIF1A bind to the 40S subunit (Plasmodium falciparum)
40S ribosomal complex [cytosol] (Plasmodium falciparum)
RPS27A(77-156) [cytosol] (Plasmodium falciparum)
40S:eIF3:eIF1A [cytosol] (Plasmodium falciparum)
40S ribosomal complex [cytosol] (Plasmodium falciparum)
RPS27A(77-156) [cytosol] (Plasmodium falciparum)
Formation of the ternary complex, and subsequently, the 43S complex (Plasmodium falciparum)
Formation of the 43S pre-initiation complex (Plasmodium falciparum)
40S:eIF3:eIF1A [cytosol] (Plasmodium falciparum)
40S ribosomal complex [cytosol] (Plasmodium falciparum)
RPS27A(77-156) [cytosol] (Plasmodium falciparum)
43S complex [cytosol] (Plasmodium falciparum)
40S ribosomal complex [cytosol] (Plasmodium falciparum)
RPS27A(77-156) [cytosol] (Plasmodium falciparum)
GTP hydrolysis and joining of the 60S ribosomal subunit (Plasmodium falciparum)
The 60S subunit joins the translation initiation complex (Plasmodium falciparum)
40S:Met-tRNAi:mRNA [cytosol] (Plasmodium falciparum)
40S ribosomal complex [cytosol] (Plasmodium falciparum)
RPS27A(77-156) [cytosol] (Plasmodium falciparum)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
40S ribosomal complex [cytosol] (Plasmodium falciparum)
RPS27A(77-156) [cytosol] (Plasmodium falciparum)
eIF5B:GTP is hydrolyzed and released (Plasmodium falciparum)
80S:Met-tRNAi:mRNA [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
40S ribosomal complex [cytosol] (Plasmodium falciparum)
RPS27A(77-156) [cytosol] (Plasmodium falciparum)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
40S ribosomal complex [cytosol] (Plasmodium falciparum)
RPS27A(77-156) [cytosol] (Plasmodium falciparum)
Ribosomal scanning and start codon recognition (Plasmodium falciparum)
Ribosomal scanning (Plasmodium falciparum)
48S complex [cytosol] (Plasmodium falciparum)
43S complex [cytosol] (Plasmodium falciparum)
40S ribosomal complex [cytosol] (Plasmodium falciparum)
RPS27A(77-156) [cytosol] (Plasmodium falciparum)
Start codon recognition (Plasmodium falciparum)
48S complex [cytosol] (Plasmodium falciparum)
43S complex [cytosol] (Plasmodium falciparum)
40S ribosomal complex [cytosol] (Plasmodium falciparum)
RPS27A(77-156) [cytosol] (Plasmodium falciparum)
L13a-mediated translational silencing of Ceruloplasmin expression (Plasmodium falciparum)
Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Plasmodium falciparum)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Plasmodium falciparum)
43S complex [cytosol] (Plasmodium falciparum)
40S ribosomal complex [cytosol] (Plasmodium falciparum)
RPS27A(77-156) [cytosol] (Plasmodium falciparum)
phospho-L13a associated wth the 3' UTR GAIT element of ceruloplasmin mRNA within the translation initiation complex [cytosol] (Plasmodium falciparum)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Plasmodium falciparum)
43S complex [cytosol] (Plasmodium falciparum)
40S ribosomal complex [cytosol] (Plasmodium falciparum)
RPS27A(77-156) [cytosol] (Plasmodium falciparum)
SRP-dependent cotranslational protein targeting to membrane (Plasmodium falciparum)
Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) (Plasmodium falciparum)
SRP:polypeptide+signal:ribosome [cytosol] (Plasmodium falciparum)
ribosome:mRNA:polypeptide+signal [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
40S ribosomal complex [cytosol] (Plasmodium falciparum)
RPS27A(77-156) [cytosol] (Plasmodium falciparum)
ribosome:mRNA:polypeptide+signal [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
40S ribosomal complex [cytosol] (Plasmodium falciparum)
RPS27A(77-156) [cytosol] (Plasmodium falciparum)
External Reference Information
External Reference
UniProt:Q8ID50
Reference Genes
BioGPS Gene:814305
ENSEMBL:PF3D7_1365900
KEGG Gene (Plasmodium falciparum):PF3D7_1365900
Monarch:814305
NCBI Gene:814305
PlasmoDB:PF3D7_1365900
Reference Transcript
RefSeq:XM_001350333.1
Participates
as an output of
UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin (Plasmodium falciparum)
as a component of
40S ribosomal complex [cytosol] (Plasmodium falciparum)
Other forms of this molecule
RPS27A(77-156) [nucleoplasm]
N6-glycyl-L-lysine-RPS27A(1-76) [cytosol]
N6-glycyl-L-lysine-UBB(153-228) [cytosol]
N6-glycyl-L-lysine-UBB(77-152) [cytosol]
phospho-adenylatedG152-UBB(77-152) [nucleoplasm]
phospho-adenylatedG228-UBB(153-228) [nucleoplasm]
phospho-adenylatedG76-UBA52(1-76) [nucleoplasm]
UBB [cytosol]
UBA52(1-128) [cytosol]
RPS27A [cytosol]
phospho-adenylatedG228-UBB(153-228) [cytosol]
phospho-adenylatedG152-UBB(77-152) [cytosol]
phospho-adenylatedG76-UBA52(1-76) [cytosol]
RPL40 [cytosol]
Ub-105-UBB(77-152) [cytosol]
Ub-181-UBB(153-228) [cytosol]
Ub-29-RPS27A(1-76) [cytosol]
Ub-158-UBB(153-228) [cytosol]
Ub-82-UBB(77-152) [cytosol]
Ub-6-RPS27A(1-76) [cytosol]
Ub-103-UBB(77-152) [cytosol]
Ub-179-UBB(153-228) [cytosol]
Ub-27-RPS27A(1-76) [cytosol]
Ub-185-UBB(153-228) [cytosol]
Ub-139-UBB(77-152) [cytosol]
Ub-215-UBB(153-228) [cytosol]
Ub-63-RPS27A(1-76) [cytosol]
RPS27A(1-76) [cytosol]
UBB(77-152) [cytosol]
UBB(153-228) [cytosol]
Ub-48-RPS27A(1-76) [cytosol]
Ub-200-UBB(153-228) [cytosol]
Ub-124-UBB(77-152) [cytosol]
Ub-63-RPS27A(1-76) [nucleoplasm]
Ub-215-UBB(153-228) [nucleoplasm]
Ub-139-UBB(77-152) [nucleoplasm]
UBB(153-228) [nucleoplasm]
RPS27A(1-76) [nucleoplasm]
UBB(77-152) [nucleoplasm]
Ub-87-UBB(77-152) [cytosol]
Ub-11-RPS27A(1-76) [cytosol]
Ub-163-UBB(153-228) [cytosol]
Ub-33-RPS27A(1-76) [cytosol]
Ub-109-UBB(77-152) [cytosol]
Inferred From
RPS27A(77-156) [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_001350369.1
PDB
3JBO
,
3JBN
,
5UMD
,
3JBP
,
3J79
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
