Reactome | RPL38 [cytosol]

RPL38 [cytosol]

Stable Identifier

R-PFA-72470

Type

Protein [EntityWithAccessionedSequence]

Species

Plasmodium falciparum

Compartment

cytosol

Synonyms

Q8II62

Locations in the PathwayBrowser

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Metabolism of RNA (Plasmodium falciparum)

- Nonsense-Mediated Decay (NMD) (Plasmodium falciparum)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Plasmodium falciparum)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Plasmodium falciparum)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Plasmodium falciparum)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Plasmodium falciparum)
        
        80S ribosome [cytosol] (Plasmodium falciparum)
        
        60S ribosomal complex [cytosol] (Plasmodium falciparum)
        
        RPL38 [cytosol] (Plasmodium falciparum)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Plasmodium falciparum)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Plasmodium falciparum)
        
        80S ribosome [cytosol] (Plasmodium falciparum)
        
        60S ribosomal complex [cytosol] (Plasmodium falciparum)
        
        RPL38 [cytosol] (Plasmodium falciparum)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Plasmodium falciparum)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Plasmodium falciparum)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Plasmodium falciparum)
        
        80S ribosome [cytosol] (Plasmodium falciparum)
        
        60S ribosomal complex [cytosol] (Plasmodium falciparum)
        
        RPL38 [cytosol] (Plasmodium falciparum)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Plasmodium falciparum)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Plasmodium falciparum)
        
        80S ribosome [cytosol] (Plasmodium falciparum)
        
        60S ribosomal complex [cytosol] (Plasmodium falciparum)
        
        RPL38 [cytosol] (Plasmodium falciparum)

External Reference Information

External Reference

UniProt:Q8II62

Reference Genes

BioGPS Gene:810859

ENSEMBL:PF3D7_1130100

KEGG Gene (Plasmodium falciparum):PF3D7_1130100

Monarch:810859

NCBI Gene:810859

PlasmoDB:PF3D7_1130100

Reference Transcript

RefSeq:XM_001347947.1

Participates

as a component of

Inferred From

RPL38 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_001347983.1

PDB

3JBP, 3J79, 5UMD, 3JBO, 3JBN