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About
What is Reactome ?
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Rbx1 [nucleoplasm]
Stable Identifier
R-RNO-1234142
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
nucleoplasm
Synonyms
RBX1, A0A0G2JUC8
Locations in the PathwayBrowser
Expand all
Cell Cycle (Rattus norvegicus)
Cell Cycle, Mitotic (Rattus norvegicus)
S Phase (Rattus norvegicus)
Synthesis of DNA (Rattus norvegicus)
Switching of origins to a post-replicative state (Rattus norvegicus)
Orc1 removal from chromatin (Rattus norvegicus)
Phosphorylated Orc1 is ubiquitinated while still associated with chromatin (Rattus norvegicus)
SCF (SKP2) complex [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular response to chemical stress (Rattus norvegicus)
KEAP1-NFE2L2 pathway (Rattus norvegicus)
Nuclear events mediated by NFE2L2 (Rattus norvegicus)
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 (Rattus norvegicus)
BTRC binds p-S344, 347 NFE2L2 (Rattus norvegicus)
BTRC:SKP1:CUL1:RBX1:p-S344, S347 NFE2L2 [nucleoplasm] (Rattus norvegicus)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1 (Rattus norvegicus)
BTRC:SKP1:CUL1:RBX1:p-S344, S347 NFE2L2 [nucleoplasm] (Rattus norvegicus)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
BTRC:SKP1:CUL1:RBX1:ub,p-S335, S338 NFE2L2 [nucleoplasm] (Rattus norvegicus)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Ub,pS335,S338,T NFE2L2 is degraded (Rattus norvegicus)
BTRC:SKP1:CUL1:RBX1:ub,p-S335, S338 NFE2L2 [nucleoplasm] (Rattus norvegicus)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Cellular response to hypoxia (Rattus norvegicus)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Rattus norvegicus)
Nuclear VBC complex ubiquitinylates HIF-alpha (Rattus norvegicus)
hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Rattus norvegicus)
VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
ub-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Rattus norvegicus)
VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Nuclear VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha (Rattus norvegicus)
VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Rattus norvegicus)
VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol (Rattus norvegicus)
ub-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Rattus norvegicus)
VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
DNA Repair (Rattus norvegicus)
DNA Damage Bypass (Rattus norvegicus)
Recognition of DNA damage by PCNA-containing replication complex (Rattus norvegicus)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Rattus norvegicus)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL [nucleoplasm] (Rattus norvegicus)
RBX1:CUL4:DDB1:DTL [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Rattus norvegicus)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL [nucleoplasm] (Rattus norvegicus)
RBX1:CUL4:DDB1:DTL [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Rattus norvegicus)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL [nucleoplasm] (Rattus norvegicus)
RBX1:CUL4:DDB1:DTL [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Rattus norvegicus)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL [nucleoplasm] (Rattus norvegicus)
RBX1:CUL4:DDB1:DTL [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Nucleotide Excision Repair (Rattus norvegicus)
Global Genome Nucleotide Excision Repair (GG-NER) (Rattus norvegicus)
DNA Damage Recognition in GG-NER (Rattus norvegicus)
PARP1 or PARP2 PARylates DDB2 and autoPARylates (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB:PARP1,PARP2 [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Rattus norvegicus)
UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
PARP1 or PARP2 binds DDB2 at GG-NER site (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Rattus norvegicus)
UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB:PARP1,PARP2 [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Rattus norvegicus)
UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
UV-DDB ubiquitinates XPC (Rattus norvegicus)
UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Rattus norvegicus)
UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Rattus norvegicus)
UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site (Rattus norvegicus)
UV-DDB:COP9 Signalosome [nucleoplasm] (Rattus norvegicus)
UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Rattus norvegicus)
UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Dual Incision in GG-NER (Rattus norvegicus)
3'-incision of DNA by ERCC5 (XPG) in GG-NER (Rattus norvegicus)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Rattus norvegicus)
PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
5'- incision of DNA by ERCC1:ERCC4 in GG-NER (Rattus norvegicus)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Rattus norvegicus)
PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
GG-NER incision complex:Open bubble dsDNA [nucleoplasm] (Rattus norvegicus)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Rattus norvegicus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Rattus norvegicus)
PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
DNA polymerases delta, epsilon or kappa bind the GG-NER site (Rattus norvegicus)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Rattus norvegicus)
PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Rattus norvegicus)
PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Formation of Incision Complex in GG-NER (Rattus norvegicus)
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER (Rattus norvegicus)
GG-NER incision complex:Open bubble dsDNA [nucleoplasm] (Rattus norvegicus)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Rattus norvegicus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Rattus norvegicus)
PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Rattus norvegicus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Rattus norvegicus)
PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
CHD1L is recruited to GG-NER site (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Formation of the pre-incision complex in GG-NER (Rattus norvegicus)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Rattus norvegicus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Rattus norvegicus)
PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Rattus norvegicus)
PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Recruitment of XPA and release of CAK (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
SUMOylation of XPC (Rattus norvegicus)
Ub,SUMO:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Rattus norvegicus)
PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
TFIIH binds GG-NER site to form a verification complex (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Rattus norvegicus)
Dual incision in TC-NER (Rattus norvegicus)
3' incision by ERCC5 (XPG) in TC-NER (Rattus norvegicus)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Rattus norvegicus)
TC-NER incision complex [nucleoplasm] (Rattus norvegicus)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Rattus norvegicus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Rattus norvegicus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Rattus norvegicus)
TC-NER incision complex [nucleoplasm] (Rattus norvegicus)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Rattus norvegicus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Rattus norvegicus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Rattus norvegicus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Rattus norvegicus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Rattus norvegicus)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
ERCC2-facilitated RNA Pol II backtracking in TC-NER (Rattus norvegicus)
TC-NER pre-incision complex [nucleoplasm] (Rattus norvegicus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Rattus norvegicus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
ERCC3-facilitated RNA Pol II backtracking in TC-NER (Rattus norvegicus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Rattus norvegicus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Rattus norvegicus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
ERCC5 and RPA bind TC-NER site (Rattus norvegicus)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Rattus norvegicus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Rattus norvegicus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Rattus norvegicus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Formation of TC-NER Pre-Incision Complex (Rattus norvegicus)
Assembly of the pre-incision complex in TC-NER (Rattus norvegicus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Rattus norvegicus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
ERCC8 (CSA) binds stalled RNA Pol II (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1:COP9 Signalosome [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
UVSSA:USP7 deubiquitinates ERCC6 (Rattus norvegicus)
TC-NER pre-incision complex [nucleoplasm] (Rattus norvegicus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Rattus norvegicus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Gap-filling DNA repair synthesis and ligation in TC-NER (Rattus norvegicus)
Ligation of newly synthesized repair patch to incised DNA in TC-NER (Rattus norvegicus)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
TC-NER post-incision complex:dsDNA with transcription bubble [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Rattus norvegicus)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
DNA Replication (Rattus norvegicus)
Synthesis of DNA (Rattus norvegicus)
Switching of origins to a post-replicative state (Rattus norvegicus)
Orc1 removal from chromatin (Rattus norvegicus)
Phosphorylated Orc1 is ubiquitinated while still associated with chromatin (Rattus norvegicus)
SCF (SKP2) complex [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Neddylation (Rattus norvegicus)
AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex (Rattus norvegicus)
NEDD8-AcM-UBE2M:CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUND1,2,4,5 [nucleoplasm] (Rattus norvegicus)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Rattus norvegicus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Rattus norvegicus)
NEDD8-CRL4 E3 ligase complex [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Rattus norvegicus)
CRL4 E3 ubiquitin ligase:CAND1 [nucleoplasm] (Rattus norvegicus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex (Rattus norvegicus)
CRL4 E3 ubiquitin ligase:CAND1 [nucleoplasm] (Rattus norvegicus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Rattus norvegicus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Rattus norvegicus)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Rattus norvegicus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Rattus norvegicus)
NEDD8-CRL4 E3 ligase complex [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex (Rattus norvegicus)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Rattus norvegicus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
NEDD8-AcM-UBE2M:CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUND1,2,4,5 [nucleoplasm] (Rattus norvegicus)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Rattus norvegicus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Signaling by Hedgehog (Rattus norvegicus)
Hedgehog 'on' state (Rattus norvegicus)
GLI2,3 are degraded by the proteasome (Rattus norvegicus)
SPOP:CUL3:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
ub-2p-GLI2,3:SPOP:CUL3:RBX1 [nucleoplasm] (Rattus norvegicus)
SPOP:CUL3:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
SPOP:CUL3:RBX1 ubiquitinates GLI2,3 (Rattus norvegicus)
2p-GLI:SPOP:CUL3:RBX1 [nucleoplasm] (Rattus norvegicus)
SPOP:CUL3:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
ub-2p-GLI2,3:SPOP:CUL3:RBX1 [nucleoplasm] (Rattus norvegicus)
SPOP:CUL3:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
phosphorylated GLI proteins bind SPOP:CUL3:RBX1 (Rattus norvegicus)
2p-GLI:SPOP:CUL3:RBX1 [nucleoplasm] (Rattus norvegicus)
SPOP:CUL3:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
SPOP:CUL3:RBX1 [nucleoplasm] (Rattus norvegicus)
Rbx1 [nucleoplasm] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:A0A0G2JUC8
Gene Names
Rbx1
Reference Genes
ENSEMBL:ENSRNOG00000058914
UCSC:A0A0G2JUC8 Rbx1
Other Identifiers
10897912
1388333_at
1388538_at
17830895
300084
5690138
5752661
6044809
6082705
6393732
6397304
6445877
A_44_P225259
A_64_P009848
GE1116548
GO:0008270
PH_rn_0006618
PH_rn_0019418
rc_AA850733_g_at
rc_AI070865_at
rc_AI072683_at
rc_AI104143_at
Participates
as a component of
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Rattus norvegicus)
NEDD8-CRL4 E3 ligase complex [nucleoplasm] (Rattus norvegicus)
RBX1:CUL4:DDB1:DTL [nucleoplasm] (Rattus norvegicus)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Rattus norvegicus)
SPOP:CUL3:RBX1 [nucleoplasm] (Rattus norvegicus)
VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Rattus norvegicus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Rattus norvegicus)
PAR-UV-DDB [nucleoplasm] (Rattus norvegicus)
UV-DDB [nucleoplasm] (Rattus norvegicus)
SCF (SKP2) complex [nucleoplasm] (Rattus norvegicus)
Other forms of this molecule
Rbx1 [cytosol]
Inferred From
RBX1 [nucleoplasm]
(Homo sapiens)
Cross References
ENSEMBL
ENSRNOP00000069049
,
ENSRNOT00000086603
RGD
1308453
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