Prlr binds Shp2

Stable Identifier
R-RNO-1369092
Type
Reaction [binding]
Species
Rattus norvegicus
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Prlr binds Shp2
Prlr can bind the protein-tyrosine Phosphatase Shp2, (Ptpn11) via its C-terminal SH2 Domain. This binding does not occur when tyrosine 599 is mutated to alanine (Ali & Ali 2000).
Literature References
Participants
Input
Output
Orthologous Events
PRLR binds SHP2 (PTPN11) (Homo sapiens)
Authored
Jupe, S  (2011-06-13)
Reviewed
Goffin, V  (2011-11-08)
Created
Jupe, S  (2011-07-04)
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