Reactome: A Curated Pathway Database

Activated thrombin:thrombomodulin cleaves PROCR:Protein C to PROCR:Activated protein C

Stable Identifier
Rattus norvegicus
protein C -> activated protein C + protein C heavy chain activation peptide
Locations in the PathwayBrowser

This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

Participant Of
This entity is regulated by:
Title Physical Entity Activity
serine-type endopeptidase activity of activated thrombin:thrombomodulin [plasma membrane] activated thrombin:thrombomodulin [plasma membrane] serine-type endopeptidase activity (0004252)
Inferred From