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Pabpc1 [cytosol]
Stable Identifier
R-RNO-156803
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
PABPC1, Q9EPH8
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Rattus norvegicus)
Deadenylation-dependent mRNA decay (Rattus norvegicus)
Deadenylation of mRNA (Rattus norvegicus)
PAN2-PAN3 complex partially deadenylates mRNA (Rattus norvegicus)
Partially Deadenylated mRNA Complex [cytosol] (Rattus norvegicus)
Pabpc1 [cytosol] (Rattus norvegicus)
Translatable mRNA Complex [cytosol] (Rattus norvegicus)
Pabpc1 [cytosol] (Rattus norvegicus)
Nonsense-Mediated Decay (NMD) (Rattus norvegicus)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Rattus norvegicus)
Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex (Rattus norvegicus)
Pabpc1 [cytosol] (Rattus norvegicus)
mRNA Cleaved by SMG6 [cytosol] (Rattus norvegicus)
Pabpc1 [cytosol] (Rattus norvegicus)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Rattus norvegicus)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Rattus norvegicus)
Pabpc1 [cytosol] (Rattus norvegicus)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Rattus norvegicus)
Pabpc1 [cytosol] (Rattus norvegicus)
SMG6 hydrolyzes mRNA with premature termination codon (Rattus norvegicus)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Rattus norvegicus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Rattus norvegicus)
Pabpc1 [cytosol] (Rattus norvegicus)
mRNA Cleaved by SMG6 [cytosol] (Rattus norvegicus)
Pabpc1 [cytosol] (Rattus norvegicus)
UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Rattus norvegicus)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Rattus norvegicus)
Pabpc1 [cytosol] (Rattus norvegicus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Rattus norvegicus)
Pabpc1 [cytosol] (Rattus norvegicus)
p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Rattus norvegicus)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Rattus norvegicus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Rattus norvegicus)
Pabpc1 [cytosol] (Rattus norvegicus)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Rattus norvegicus)
Pabpc1 [cytosol] (Rattus norvegicus)
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Rattus norvegicus)
Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Rattus norvegicus)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Rattus norvegicus)
mRNA Complex with a Premature Termination Codon Not Preceding an Exon Junction [cytosol] (Rattus norvegicus)
Pabpc1 [cytosol] (Rattus norvegicus)
UPF1:eRF3 Complex on Translated mRNA [cytosol] (Rattus norvegicus)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Rattus norvegicus)
mRNA Complex with a Premature Termination Codon Not Preceding an Exon Junction [cytosol] (Rattus norvegicus)
Pabpc1 [cytosol] (Rattus norvegicus)
Regulation of mRNA stability by proteins that bind AU-rich elements (Rattus norvegicus)
AUF1 (hnRNP D0) binds and destabilizes mRNA (Rattus norvegicus)
AUF1 (hnRNP D0) is ubiquitinylated (Rattus norvegicus)
AUF1 Complexed with Translation and Heat Shock Proteins [cytosol] (Rattus norvegicus)
Pabpc1 [cytosol] (Rattus norvegicus)
AUF1 binds translation and heat shock proteins (Rattus norvegicus)
AUF1 Complexed with Translation and Heat Shock Proteins [cytosol] (Rattus norvegicus)
Pabpc1 [cytosol] (Rattus norvegicus)
Pabpc1 [cytosol] (Rattus norvegicus)
Metabolism of proteins (Rattus norvegicus)
Translation (Rattus norvegicus)
Eukaryotic Translation Initiation (Rattus norvegicus)
Cap-dependent Translation Initiation (Rattus norvegicus)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Rattus norvegicus)
Translation initiation complex formation (Rattus norvegicus)
Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation (Rattus norvegicus)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Rattus norvegicus)
Pabpc1 [cytosol] (Rattus norvegicus)
Pabpc1 [cytosol] (Rattus norvegicus)
L13a-mediated translational silencing of Ceruloplasmin expression (Rattus norvegicus)
Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Rattus norvegicus)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Rattus norvegicus)
Pabpc1 [cytosol] (Rattus norvegicus)
phospho-L13a associated wth the 3' UTR GAIT element of ceruloplasmin mRNA within the translation initiation complex [cytosol] (Rattus norvegicus)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Rattus norvegicus)
Pabpc1 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:Q9EPH8
Gene Names
Pabpc1
Reference Genes
BioGPS Gene:171350 Pabpc1
ENSEMBL:ENSRNOG00000008639
ENSEMBL:ENSRNOG00000008639.8 Pabpc1
ENSEMBL:ENSRNOG00055023445
ENSEMBL:ENSRNOG00060008612
ENSEMBL:ENSRNOG00065003631
KEGG Gene (Rattus norvegicus):171350 Pabpc1
Monarch:171350 Pabpc1
NCBI Gene:171350 Pabpc1
UCSC:Q9EPH8 Pabpc1
Reference Transcript
RefSeq:NM_134353.3 Pabpc1
Other Identifiers
10903346
1369952_at
171350
17836875
5675924
5700325
5707037
5721778
5725050
5769750
5819954
5933937
5954976
6001356
6027845
6166549
6166648
6217492
6227227
6308208
6315206
6332516
6412655
6434163
6457463
A_43_P13245
A_64_P052137
GO:0003676
GO:0003723
GO:0005737
GO:0016071
GO:0031047
GO:0045202
GO:0060213
GO:1900153
PH_rn_0018627
rc_AA899197_at
Participates
as an input of
AUF1 binds translation and heat shock proteins (Rattus norvegicus)
Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation (Rattus norvegicus)
as a component of
AUF1 Complexed with Translation and Heat Shock Proteins [cytosol] (Rattus norvegicus)
mRNA Cleaved by SMG6 [cytosol] (Rattus norvegicus)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Rattus norvegicus)
mRNA Complex with a Premature Termination Codon Not Preceding an Exon Junction [cytosol] (Rattus norvegicus)
Partially Deadenylated mRNA Complex [cytosol] (Rattus norvegicus)
Translatable mRNA Complex [cytosol] (Rattus norvegicus)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Rattus norvegicus)
as an output of
Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex (Rattus norvegicus)
Inferred From
PABPC1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_599180.1
Ensembl
ENSRNOG00000008639
,
ENSRNOP00000012775
,
ENSRNOT00000012775
PRO
Q9EPH8
RGD
619838
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q01728
1
SLC8A1 [plasma membrane]
(R-RNO-425681)
0.462
2
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