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Nuclear Pore Complex (NPC) [nuclear envelope]
Stable Identifier
R-RNO-157689
Type
Complex
Species
Rattus norvegicus
Compartment
nuclear envelope
Locations in the PathwayBrowser
Expand all
Cell Cycle (Rattus norvegicus)
Cell Cycle, Mitotic (Rattus norvegicus)
M Phase (Rattus norvegicus)
Mitotic Prophase (Rattus norvegicus)
Nuclear Envelope Breakdown (Rattus norvegicus)
Nuclear Pore Complex (NPC) Disassembly (Rattus norvegicus)
CDK1 phosphorylates NUP98 (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular response to heat stress (Rattus norvegicus)
Regulation of HSF1-mediated heat shock response (Rattus norvegicus)
NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
Gene expression (Transcription) (Rattus norvegicus)
Gene Silencing by RNA (Rattus norvegicus)
Transcriptional regulation by small RNAs (Rattus norvegicus)
Importin-8 imports AGO2:miRNA into the nucleus (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
Metabolism (Rattus norvegicus)
Metabolism of carbohydrates (Rattus norvegicus)
Glucose metabolism (Rattus norvegicus)
Glycolysis (Rattus norvegicus)
Regulation of Glucokinase by Glucokinase Regulatory Protein (Rattus norvegicus)
NPC transports GCK1:GKRP from cytosol to nucleoplasm (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
Metabolism of RNA (Rattus norvegicus)
Metabolism of non-coding RNA (Rattus norvegicus)
snRNP Assembly (Rattus norvegicus)
snRNP nuclear import and release (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
Processing of Capped Intron-Containing Pre-mRNA (Rattus norvegicus)
Transport of Mature Transcript to Cytoplasm (Rattus norvegicus)
Transport of Mature mRNA derived from an Intron-Containing Transcript (Rattus norvegicus)
Transport of the export-competent mRNP complex through the NPC (Rattus norvegicus)
NPC:NXF1,2:NXT1:EJC:CBC:mRNA [nucleoplasm] (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol] (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
mRNP complex dissociates from cytosolic face of NPC (Rattus norvegicus)
NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol] (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
Transport of Mature mRNAs Derived from Intronless Transcripts (Rattus norvegicus)
Transport of Mature mRNA Derived from an Intronless Transcript (Rattus norvegicus)
Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
Transport of the SLBP Dependant Mature mRNA (Rattus norvegicus)
Docking of Mature Replication Dependent Histone mRNA with the NPC (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
Transport of the SLBP independent Mature mRNA (Rattus norvegicus)
Docking of Mature Histone mRNA complex:TAP at the NPC (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
Release of the SLBP independent Histone mRNA from the NPC (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
SUMOylation (Rattus norvegicus)
SUMO E3 ligases SUMOylate target proteins (Rattus norvegicus)
SUMOylation of DNA damage response and repair proteins (Rattus norvegicus)
RANBP2 SUMOylates PML with SUMO1 (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
RANBP2 SUMOylates PML with SUMO2 (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
RANBP2 SUMOylates SP100 with SUMO1 (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
RANBP2 SUMOylates SP100 with SUMO2 (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
SUMOylation of RNA binding proteins (Rattus norvegicus)
RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
SUMOylation of SUMOylation proteins (Rattus norvegicus)
RANBP2 SUMOylates RANBP2 with SUMO1 (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
RANBP2 SUMOylates RANBP2 with SUMO2 (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
SUMOylation of chromatin organization proteins (Rattus norvegicus)
RANBP2 SUMOylates HDAC4 with SUMO1 (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
RANBP2 SUMOylates HDAC4 with SUMO2,3 (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
SUMOylation of ubiquitinylation proteins (Rattus norvegicus)
RANBP2 SUMOylates MDM2 with SUMO1 (Rattus norvegicus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Rattus norvegicus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 8
Aaas [nuclear envelope]
(Rattus norvegicus)
x 16
Ghost homologue of SEH1L-2 [nuclear envelope]
(Rattus norvegicus)
x 32
Ndc1 [nuclear envelope]
(Rattus norvegicus)
x 32
Nup107-160 complex [cytosol]
(Rattus norvegicus)
x 8
NUP153 [nucleoplasm]
(Rattus norvegicus)
x 16
Nup188 [nuclear envelope]
(Rattus norvegicus)
x 16
Nup210 [nuclear envelope]
(Rattus norvegicus)
x 8
Nup214 [cytosol]
(Rattus norvegicus)
x 16
Nup42 [cytosol]
(Rattus norvegicus)
x 32
Nup50 [nucleoplasm]
(Rattus norvegicus)
x 32
Nup62 Complex [nuclear envelope]
(Rattus norvegicus)
x 32
Nup88 [cytosol]
(Rattus norvegicus)
x 32
Nup93 complex [nuclear envelope]
(Rattus norvegicus)
x 8
Nup98 [nuclear envelope]
(Rattus norvegicus)
x 16
Pom121 [nuclear envelope]
(Rattus norvegicus)
x 48
Rae1 [nuclear envelope]
(Rattus norvegicus)
x 8
Ranbp2 [cytosol]
(Rattus norvegicus)
x 16
Tpr [nucleoplasm]
(Rattus norvegicus)
Participates
as an output of
mRNP complex dissociates from cytosolic face of NPC (Rattus norvegicus)
as a component of
NPC:NXF1,2:NXT1:EJC:CBC:mRNA [nucleoplasm] (Rattus norvegicus)
NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol] (Rattus norvegicus)
as an input of
CDK1 phosphorylates NUP98 (Rattus norvegicus)
This entity regulates
Positively
snRNP nuclear import and release
(Rattus norvegicus)
Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC
(Rattus norvegicus)
Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC
(Rattus norvegicus)
Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC
(Rattus norvegicus)
Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex
(Rattus norvegicus)
Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC
(Rattus norvegicus)
Docking of Mature Replication Dependent Histone mRNA with the NPC
(Rattus norvegicus)
Release of the SLBP independent Histone mRNA from the NPC
(Rattus norvegicus)
Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC
(Rattus norvegicus)
Docking of Mature Histone mRNA complex:TAP at the NPC
(Rattus norvegicus)
mRNP complex dissociates from cytosolic face of NPC
(Rattus norvegicus)
Transport of the export-competent mRNP complex through the NPC
(Rattus norvegicus)
Inferred From
Nuclear Pore Complex (NPC) [nuclear envelope]
(Homo sapiens)
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