Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
CHUK:IKBKB:IKBKG [cytosol]
Stable Identifier
R-RNO-168113
Type
Complex
Species
Rattus norvegicus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Rattus norvegicus)
Adaptive Immune System (Rattus norvegicus)
TCR signaling (Rattus norvegicus)
Downstream TCR signaling (Rattus norvegicus)
Activation of IKK complex (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
Cytokine Signaling in Immune system (Rattus norvegicus)
Interferon Signaling (Rattus norvegicus)
Antiviral mechanism by IFN-stimulated genes (Rattus norvegicus)
PKR-mediated signaling (Rattus norvegicus)
IKK complex is activated by PKR (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
Signaling by Interleukins (Rattus norvegicus)
Interleukin-1 family signaling (Rattus norvegicus)
Interleukin-1 signaling (Rattus norvegicus)
NEMO binds polyubiquitinated IRAK1 (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
Poly-K6-Ub-hp-IRAK1:CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
CHUK, IKBKB and IKBKG form IKK complex (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
Regulation of NF-kappa B signaling (Rattus norvegicus)
NLRX1 binds CHUK:IKBKB:IKBKG (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG:K63polyUb-NLRX1 [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
USP18 binds IKBKG within IKK complex (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
Innate Immune System (Rattus norvegicus)
C-type lectin receptors (CLRs) (Rattus norvegicus)
CLEC7A (Dectin-1) signaling (Rattus norvegicus)
K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
Fc epsilon receptor (FCERI) signaling (Rattus norvegicus)
FCERI mediated NF-kB activation (Rattus norvegicus)
Phosphorylation of IKK-beta by TAK1 (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
Toll-like Receptor Cascades (Rattus norvegicus)
Toll Like Receptor 10 (TLR10) Cascade (Rattus norvegicus)
MyD88 cascade initiated on plasma membrane (Rattus norvegicus)
IRAK1 recruits IKK complex (Rattus norvegicus)
NEMO subunit of IKK complex binds to activated IRAK1 (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
CHUK, IKBKB and IKBKG form IKK complex (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
Regulation of NF-kappa B signaling (Rattus norvegicus)
NLRX1 binds CHUK:IKBKB:IKBKG (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG:K63polyUb-NLRX1 [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
USP18 binds IKBKG within IKK complex (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
Toll Like Receptor 2 (TLR2) Cascade (Rattus norvegicus)
Toll Like Receptor TLR1:TLR2 Cascade (Rattus norvegicus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
IRAK1 recruits IKK complex (Rattus norvegicus)
NEMO subunit of IKK complex binds to activated IRAK1 (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
CHUK, IKBKB and IKBKG form IKK complex (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
Regulation of NF-kappa B signaling (Rattus norvegicus)
NLRX1 binds CHUK:IKBKB:IKBKG (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG:K63polyUb-NLRX1 [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
USP18 binds IKBKG within IKK complex (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
Toll Like Receptor TLR6:TLR2 Cascade (Rattus norvegicus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
IRAK1 recruits IKK complex (Rattus norvegicus)
NEMO subunit of IKK complex binds to activated IRAK1 (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
CHUK, IKBKB and IKBKG form IKK complex (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
Regulation of NF-kappa B signaling (Rattus norvegicus)
NLRX1 binds CHUK:IKBKB:IKBKG (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG:K63polyUb-NLRX1 [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
USP18 binds IKBKG within IKK complex (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
Toll Like Receptor 3 (TLR3) Cascade (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
CHUK, IKBKB and IKBKG form IKK complex (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
Regulation of NF-kappa B signaling (Rattus norvegicus)
NLRX1 binds CHUK:IKBKB:IKBKG (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG:K63polyUb-NLRX1 [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
USP18 binds IKBKG within IKK complex (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
Toll Like Receptor 4 (TLR4) Cascade (Rattus norvegicus)
MyD88-independent TLR4 cascade (Rattus norvegicus)
TRIF (TICAM1)-mediated TLR4 signaling (Rattus norvegicus)
IKK complex recruitment mediated by RIP1 (Rattus norvegicus)
IKBKG subunit of IKK complex binds polyubiquinated RIP1 (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG:K63pUb-RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
CHUK, IKBKB and IKBKG form IKK complex (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
Regulation of NF-kappa B signaling (Rattus norvegicus)
NLRX1 binds CHUK:IKBKB:IKBKG (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG:K63polyUb-NLRX1 [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
USP18 binds IKBKG within IKK complex (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
IRAK1 recruits IKK complex (Rattus norvegicus)
NEMO subunit of IKK complex binds to activated IRAK1 (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
CHUK, IKBKB and IKBKG form IKK complex (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
Regulation of NF-kappa B signaling (Rattus norvegicus)
NLRX1 binds CHUK:IKBKB:IKBKG (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG:K63polyUb-NLRX1 [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
USP18 binds IKBKG within IKK complex (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
Toll Like Receptor 5 (TLR5) Cascade (Rattus norvegicus)
MyD88 cascade initiated on plasma membrane (Rattus norvegicus)
IRAK1 recruits IKK complex (Rattus norvegicus)
NEMO subunit of IKK complex binds to activated IRAK1 (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
CHUK, IKBKB and IKBKG form IKK complex (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
Regulation of NF-kappa B signaling (Rattus norvegicus)
NLRX1 binds CHUK:IKBKB:IKBKG (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG:K63polyUb-NLRX1 [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
USP18 binds IKBKG within IKK complex (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Rattus norvegicus)
MyD88 dependent cascade initiated on endosome (Rattus norvegicus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Rattus norvegicus)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Rattus norvegicus)
NEMO subunit of IKK complex binds to activated IRAK1 upon stimulation of TLR7/8 or 9. (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [endosome membrane] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
CHUK, IKBKB and IKBKG form IKK complex (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
Regulation of NF-kappa B signaling (Rattus norvegicus)
NLRX1 binds CHUK:IKBKB:IKBKG (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG:K63polyUb-NLRX1 [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
USP18 binds IKBKG within IKK complex (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
Toll Like Receptor 9 (TLR9) Cascade (Rattus norvegicus)
MyD88 dependent cascade initiated on endosome (Rattus norvegicus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Rattus norvegicus)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Rattus norvegicus)
NEMO subunit of IKK complex binds to activated IRAK1 upon stimulation of TLR7/8 or 9. (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [endosome membrane] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
CHUK, IKBKB and IKBKG form IKK complex (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
Regulation of NF-kappa B signaling (Rattus norvegicus)
NLRX1 binds CHUK:IKBKB:IKBKG (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG:K63polyUb-NLRX1 [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
USP18 binds IKBKG within IKK complex (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Death Receptor Signaling (Rattus norvegicus)
TNF signaling (Rattus norvegicus)
Regulation of TNFR1 signaling (Rattus norvegicus)
GNB2L1 binds IKKA:IKKB:NEMO (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
IKKA:IKKB:NEMO:GNB2L1 [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
TNFR1-induced NF-kappa-B signaling pathway (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
TNFα:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2/3:CHUK:IKBKB:IKBKG [plasma membrane] (Rattus norvegicus)
CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
CHUK [cytosol]
(Rattus norvegicus)
Homologues of IKBKG [cytosol]
(Rattus norvegicus)
IKBKB [cytosol]
(Rattus norvegicus)
Participates
as an input of
IKK complex is activated by PKR (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG (Rattus norvegicus)
GNB2L1 binds IKKA:IKKB:NEMO (Rattus norvegicus)
NEMO subunit of IKK complex binds to activated IRAK1 upon stimulation of TLR7/8 or 9. (Rattus norvegicus)
NEMO binds polyubiquitinated IRAK1 (Rattus norvegicus)
K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta (Rattus norvegicus)
Activation of IKK complex (Rattus norvegicus)
Phosphorylation of IKK-beta by TAK1 (Rattus norvegicus)
IKBKG subunit of IKK complex binds polyubiquinated RIP1 (Rattus norvegicus)
NLRX1 binds CHUK:IKBKB:IKBKG (Rattus norvegicus)
USP18 binds IKBKG within IKK complex (Rattus norvegicus)
NEMO subunit of IKK complex binds to activated IRAK1 (Rattus norvegicus)
as a component of
TNFα:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2/3:CHUK:IKBKB:IKBKG [plasma membrane] (Rattus norvegicus)
IKKA:IKKB:NEMO:GNB2L1 [cytosol] (Rattus norvegicus)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [endosome membrane] (Rattus norvegicus)
Poly-K6-Ub-hp-IRAK1:CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG:K63pUb-RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
CHUK:IKBKB:IKBKG:K63polyUb-NLRX1 [cytosol] (Rattus norvegicus)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Rattus norvegicus)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [cytosol] (Rattus norvegicus)
as an output of
CHUK, IKBKB and IKBKG form IKK complex (Rattus norvegicus)
Inferred From
CHUK:IKBKB:IKBKG [cytosol]
(Homo sapiens)
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text