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phospho-p-4S,T185,T186-TGFBR1 [plasma membrane]
Stable Identifier
R-RNO-170849
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
plasma membrane
Synonyms
P80204
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
Signaling by TGFB family members (Rattus norvegicus)
Signaling by TGF-beta Receptor Complex (Rattus norvegicus)
TGF-beta receptor signaling activates SMADs (Rattus norvegicus)
Activated type I receptor phosphorylates SMAD2/3 directly (Rattus norvegicus)
TGFB1:p-TGFBR:ZFYVE9:SMAD2/3 [early endosome membrane] (Rattus norvegicus)
p-TGFBR1 [plasma membrane] (Rattus norvegicus)
phospho-p-4S,T185,T186-TGFBR1 [plasma membrane] (Rattus norvegicus)
TGFB1:p-TGFBR:ZFYVE9:p-2S-SMAD2,3 [early endosome membrane] (Rattus norvegicus)
p-TGFBR1 [plasma membrane] (Rattus norvegicus)
phospho-p-4S,T185,T186-TGFBR1 [plasma membrane] (Rattus norvegicus)
p-TGFBR1 [plasma membrane] (Rattus norvegicus)
phospho-p-4S,T185,T186-TGFBR1 [plasma membrane] (Rattus norvegicus)
An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
p-TGFBR1 [plasma membrane] (Rattus norvegicus)
phospho-p-4S,T185,T186-TGFBR1 [plasma membrane] (Rattus norvegicus)
TGFB1:p-TGFBR:ZFYVE9:SMAD2/3 [early endosome membrane] (Rattus norvegicus)
p-TGFBR1 [plasma membrane] (Rattus norvegicus)
phospho-p-4S,T185,T186-TGFBR1 [plasma membrane] (Rattus norvegicus)
Downregulation of TGF-beta receptor signaling (Rattus norvegicus)
BAMBI interferes with the interaction of type I receptor with type II receptor (Rattus norvegicus)
TGFB1: TGFBR2: p-TGFBR1: BAMBI: SMAD7 [plasma membrane] (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
p-TGFBR1 [plasma membrane] (Rattus norvegicus)
phospho-p-4S,T185,T186-TGFBR1 [plasma membrane] (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
p-TGFBR1 [plasma membrane] (Rattus norvegicus)
phospho-p-4S,T185,T186-TGFBR1 [plasma membrane] (Rattus norvegicus)
Degradation of TGF-beta receptor complex (Rattus norvegicus)
TGFB1:TGFBR2:Ub-p-TGFBR1:Ub-SMAD7 [plasma membrane] (Rattus norvegicus)
TGFB1: p-TGFBR: I-SMAD7 [plasma membrane] (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
p-TGFBR1 [plasma membrane] (Rattus norvegicus)
phospho-p-4S,T185,T186-TGFBR1 [plasma membrane] (Rattus norvegicus)
I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) (Rattus norvegicus)
TGFB1: p-TGFBR: I-SMAD7 [plasma membrane] (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
p-TGFBR1 [plasma membrane] (Rattus norvegicus)
phospho-p-4S,T185,T186-TGFBR1 [plasma membrane] (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
p-TGFBR1 [plasma membrane] (Rattus norvegicus)
phospho-p-4S,T185,T186-TGFBR1 [plasma membrane] (Rattus norvegicus)
STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 (Rattus norvegicus)
TGFB1: p-TGFBR: STRAP: SMAD7 [plasma membrane] (Rattus norvegicus)
TGFB1:p-TGFBR:STRAP [plasma membrane] (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
p-TGFBR1 [plasma membrane] (Rattus norvegicus)
phospho-p-4S,T185,T186-TGFBR1 [plasma membrane] (Rattus norvegicus)
TGFB1:p-TGFBR:STRAP [plasma membrane] (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
p-TGFBR1 [plasma membrane] (Rattus norvegicus)
phospho-p-4S,T185,T186-TGFBR1 [plasma membrane] (Rattus norvegicus)
Phosphorylated SMAD2/3 dissociates from TGFBR (Rattus norvegicus)
TGFB1:p-TGFBR:ZFYVE9 [early endosome membrane] (Rattus norvegicus)
p-TGFBR1 [plasma membrane] (Rattus norvegicus)
phospho-p-4S,T185,T186-TGFBR1 [plasma membrane] (Rattus norvegicus)
TGFB1:p-TGFBR:ZFYVE9:p-2S-SMAD2,3 [early endosome membrane] (Rattus norvegicus)
p-TGFBR1 [plasma membrane] (Rattus norvegicus)
phospho-p-4S,T185,T186-TGFBR1 [plasma membrane] (Rattus norvegicus)
TGFBR2 phosphorylates TGFBR1 (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
p-TGFBR1 [plasma membrane] (Rattus norvegicus)
phospho-p-4S,T185,T186-TGFBR1 [plasma membrane] (Rattus norvegicus)
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) (Rattus norvegicus)
Disassembly of tight junctions (Rattus norvegicus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Rattus norvegicus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Rattus norvegicus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
p-TGFBR1 [plasma membrane] (Rattus norvegicus)
phospho-p-4S,T185,T186-TGFBR1 [plasma membrane] (Rattus norvegicus)
SMURF1 binds phosphorylated PARD6A (Rattus norvegicus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
p-TGFBR1 [plasma membrane] (Rattus norvegicus)
phospho-p-4S,T185,T186-TGFBR1 [plasma membrane] (Rattus norvegicus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Rattus norvegicus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
p-TGFBR1 [plasma membrane] (Rattus norvegicus)
phospho-p-4S,T185,T186-TGFBR1 [plasma membrane] (Rattus norvegicus)
SMURF1 ubiquitinates RHOA (Rattus norvegicus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Rattus norvegicus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
p-TGFBR1 [plasma membrane] (Rattus norvegicus)
phospho-p-4S,T185,T186-TGFBR1 [plasma membrane] (Rattus norvegicus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Rattus norvegicus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Rattus norvegicus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
p-TGFBR1 [plasma membrane] (Rattus norvegicus)
phospho-p-4S,T185,T186-TGFBR1 [plasma membrane] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P80204
Reference Genes
BioGPS Gene:29591
ENSEMBL:ENSRNOG00000007036
ENSEMBL:ENSRNOG00000050760
Monarch:29591
NCBI Gene:29591
UCSC:P80204
Reference Transcript
RefSeq:XM_006238030.3
Participates
as a component of
p-TGFBR1 [plasma membrane] (Rattus norvegicus)
Other forms of this molecule
Ub-TGFBR1 [plasma membrane]
TGFBR1 [plasma membrane]
Inferred From
p-4S,T185,T186-TGFBR1 [plasma membrane]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 165 (in Homo sapiens)
Coordinate
165
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 185 (in Homo sapiens)
Coordinate
185
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-threonine at 186 (in Homo sapiens)
Coordinate
186
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 187 (in Homo sapiens)
Coordinate
187
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 189 (in Homo sapiens)
Coordinate
189
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 191 (in Homo sapiens)
Coordinate
191
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
XP_006238092.2
IntEnz
2.7.11.30
PRO
P80204
RGD
3852
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