Reactome | NGFR(251-427) [plasma membrane]

NGFR(251-427) [plasma membrane]

Stable Identifier

R-RNO-194476

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

P07174

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P07174 Ngfr

Gene Names

Ngfr, Tnfrsf16

Chain

signal peptide:1-29, chain:30-425

Reference Genes

BioGPS Gene:24596 Ngfr

dbSNP Gene:24596 Ngfr

KEGG Gene (Rattus norvegicus):24596 Ngfr

Monarch:24596 Ngfr

NCBI Gene:24596 Ngfr

UCSC:P07174 Ngfr

Reference Transcript

RefSeq:NM_012610.2 Ngfr

Participant Of

input

output

alpha-secretase cleaves the p75NTR extracellular domain

Other forms of this molecule

Tumor necrosis factor receptor superfamily member 16 [plasma membrane]

NGFR(273-427) [nucleoplasm]

NGFR(251-272) [plasma membrane]

NGFR(273-427) [cytosol]

NGFR(29-250) [extracellular region]

NGFR [plasma membrane]

NGFR(251-427) [endosome]

Inferred From

NGFR(251-427) [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_036742.2

PRO

P07174

PDB

3IJ2, 2MJO, 2MIC, 4F42, 1NGR, 1SG1, 4F44, 3BUK

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P01138 NGF	7	NGF(19-241) [extracellular region] (R-HSA-187033) NGF [Golgi lumen] (R-HSA-166515) NGF [cytosol] (R-HSA-190059) NGF(1-241) [endoplasmic reticulum lumen] (R-HSA-187026) NGF(19-241) [Golgi lumen] (R-HSA-187036) NGF(19-241) [endoplasmic reticulum lumen] (R-HSA-187047) NGF [extracellular region] (R-HSA-167034)	0.722	3
UniProt:P20783 NTF3	1	NTF3 [extracellular region] (R-HSA-167062)	0.655	4
UniProt:P07174 Ngfr	8	NGFR(273-427) [nucleoplasm] (R-RNO-197473) Tumor necrosis factor receptor superfamily member 16 [plasma membrane] (R-RNO-193863) NGFR(251-272) [plasma membrane] (R-RNO-194509) NGFR(273-427) [cytosol] (R-RNO-194458) NGFR(29-250) [extracellular region] (R-RNO-194470) NGFR [plasma membrane] (R-RNO-193664) NGFR(251-427) [endosome] (R-RNO-209541) NGFR(251-427) [plasma membrane] (R-RNO-194476)	0.609	2
UniProt:Q3MKQ2 BEX1			0.591	4
UniProt:Q9Y4K3 TRAF6	8	K63polyUb-TRAF6 [cytosol] (R-HSA-2685681) TRAF6 [cytosol] (R-HSA-166366) K63polyUb-TRAF6 [plasma membrane] (R-HSA-936980) TRAF6 [plasma membrane] (R-HSA-936955) K63polyUb-TRAF6 [endosome membrane] (R-HSA-450227) TRAF6 [endosome membrane] (R-HSA-450272) PolyUb-TRAF6 [cytosol] (R-HSA-6782845) K48polyUb-TRAF6 [cytosol] (R-HSA-6783233)	0.589	2
UniProt:Q12933 TRAF2	5	K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) TRAF2 [nucleoplasm] (R-HSA-8862199) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) TRAF2 [cytosol] (R-HSA-66370) PolyUb-TRAF2 [cytosol] (R-HSA-6782848)	0.524	3
UniProt:Q9BUZ4 TRAF4			0.524	3