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Tiam1 [cytosol]
Stable Identifier
R-RNO-195013
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
TIAM1, A0A8I6AC12
Locations in the PathwayBrowser
Expand all
Developmental Biology (Rattus norvegicus)
Nervous system development (Rattus norvegicus)
Axon guidance (Rattus norvegicus)
EPH-Ephrin signaling (Rattus norvegicus)
EPH-ephrin mediated repulsion of cells (Rattus norvegicus)
EPHA binds TIAM1 (Rattus norvegicus)
EFNAs:p-EPHAs:SFKs:TIAM1 [plasma membrane] (Rattus norvegicus)
Tiam1 [cytosol] (Rattus norvegicus)
Tiam1 [cytosol] (Rattus norvegicus)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Rattus norvegicus)
EFNAs:p-EPHAs:SFKs:TIAM1 [plasma membrane] (Rattus norvegicus)
Tiam1 [cytosol] (Rattus norvegicus)
EPHB-mediated forward signaling (Rattus norvegicus)
EPHB phosphorylates TIAM1 (Rattus norvegicus)
EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly:TIAM1 [plasma membrane] (Rattus norvegicus)
Tiam1 [cytosol] (Rattus norvegicus)
EPHB:NMDAR binds TIAM1 (Rattus norvegicus)
EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly:TIAM1 [plasma membrane] (Rattus norvegicus)
Tiam1 [cytosol] (Rattus norvegicus)
Tiam1 [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Death Receptor Signaling (Rattus norvegicus)
p75 NTR receptor-mediated signalling (Rattus norvegicus)
Cell death signalling via NRAGE, NRIF and NADE (Rattus norvegicus)
NRAGE signals death through JNK (Rattus norvegicus)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Rattus norvegicus)
GEFs [cytosol] (Rattus norvegicus)
Tiam1 [cytosol] (Rattus norvegicus)
Signaling by GPCR (Rattus norvegicus)
GPCR downstream signalling (Rattus norvegicus)
G alpha (12/13) signalling events (Rattus norvegicus)
GEFs activate RhoA,B,C (Rattus norvegicus)
GEFs [cytosol] (Rattus norvegicus)
Tiam1 [cytosol] (Rattus norvegicus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Rattus norvegicus)
Signaling by Rho GTPases (Rattus norvegicus)
RHO GTPase cycle (Rattus norvegicus)
CDC42 GTPase cycle (Rattus norvegicus)
CDC42 GEFs activate CDC42 (Rattus norvegicus)
CDC42 GEFs [cytosol] (Rattus norvegicus)
Tiam1 [cytosol] (Rattus norvegicus)
RAC1 GTPase cycle (Rattus norvegicus)
RAC1 GEFs activate RAC1 (Rattus norvegicus)
RAC1 GEFs [cytosol] (Rattus norvegicus)
Tiam1 [cytosol] (Rattus norvegicus)
RAC2 GTPase cycle (Rattus norvegicus)
RAC2 GEFs activate RAC2 (Rattus norvegicus)
RAC2 GEFs [cytosol] (Rattus norvegicus)
Tiam1 [cytosol] (Rattus norvegicus)
RHOA GTPase cycle (Rattus norvegicus)
RHOA GEFs activate RHOA (Rattus norvegicus)
RHOA GEFs [cytosol] (Rattus norvegicus)
Tiam1 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:A0A8I6AC12
Gene Names
Tiam1
Reference Genes
BioGPS Gene:304109 Tiam1
ENSEMBL:ENSRNOG00000021569
ENSEMBL:ENSRNOG00000021569.7 Tiam1
KEGG Gene (Rattus norvegicus):304109 Tiam1
Monarch:304109 Tiam1
NCBI Gene:304109 Tiam1
Reference Transcript
RefSeq:NM_001100558.1 Tiam1
Other Identifiers
10750144
1374257_at
1377591_at
1381167_at
1392980_at
17664575
304109
5640301
5671955
5696140
5698441
5723784
5786833
5858745
5929652
5981873
6038462
6050972
6064372
6086530
6152717
6207467
6218355
6238402
6246725
6258811
6273040
6317850
6398208
6410130
6417567
6456788
6465526
6470812
6522367
6569628
6573016
6600525
6739465
A_44_P104271
A_44_P314492
GE1193711
GE15652
GE17579
GE18916
GO:0005085
GO:0005515
GO:0005829
GO:0005886
GO:0005911
GO:0007155
GO:0007160
GO:0007165
GO:0007264
GO:0008284
GO:0010717
GO:0016477
GO:0016601
GO:0019900
GO:0023052
GO:0030154
GO:0030335
GO:0035556
GO:0044291
GO:0048856
GO:0048870
GO:0065003
GO:0090630
GO:0098772
ILMN_1349837
PH_rn_0014353
PH_rn_0021806
Participates
as a candidate of
RHOA GEFs [cytosol] (Rattus norvegicus)
CDC42 GEFs [cytosol] (Rattus norvegicus)
RAC1 GEFs [cytosol] (Rattus norvegicus)
as a member of
RAC2 GEFs [cytosol] (Rattus norvegicus)
GEFs [cytosol] (Rattus norvegicus)
as an input of
EPHB:NMDAR binds TIAM1 (Rattus norvegicus)
EPHA binds TIAM1 (Rattus norvegicus)
as a component of
EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly:TIAM1 [plasma membrane] (Rattus norvegicus)
EFNAs:p-EPHAs:SFKs:TIAM1 [plasma membrane] (Rattus norvegicus)
Other forms of this molecule
phospho-Tiam1 [cytosol]
Inferred From
TIAM1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001094028.1
Ensembl
ENSRNOP00000089482
,
ENSRNOG00000021569
,
ENSRNOT00000109567
RGD
1307455
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