Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Srgap2 [cytosol]
Stable Identifier
R-RNO-195131
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
SRGAP2, D4A208
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Rattus norvegicus)
Signaling by Rho GTPases (Rattus norvegicus)
RHO GTPase Effectors (Rattus norvegicus)
RHO GTPases Activate Formins (Rattus norvegicus)
SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin (Rattus norvegicus)
SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Rattus norvegicus)
Srgap2 [cytosol] (Rattus norvegicus)
Srgap2 [cytosol] (Rattus norvegicus)
SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments (Rattus norvegicus)
SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Rattus norvegicus)
Srgap2 [cytosol] (Rattus norvegicus)
Srgap2 [cytosol] (Rattus norvegicus)
RHO GTPase cycle (Rattus norvegicus)
CDC42 GTPase cycle (Rattus norvegicus)
CDC42 GAPs stimulate CDC42 GTPase activity (Rattus norvegicus)
CDC42 GAPs [cytosol] (Rattus norvegicus)
Srgap2 [cytosol] (Rattus norvegicus)
RAC1 GTPase cycle (Rattus norvegicus)
RAC1 GAPs stimulate RAC1 GTPase activity (Rattus norvegicus)
RAC1 GAPs [cytosol] (Rattus norvegicus)
Srgap2 [cytosol] (Rattus norvegicus)
RHOF GTPase cycle (Rattus norvegicus)
RHOF GAPs stimulate RHOF GTPase activity (Rattus norvegicus)
RHOF GAPs [cytosol] (Rattus norvegicus)
Srgap2 [cytosol] (Rattus norvegicus)
RHOQ GTPase cycle (Rattus norvegicus)
RHOQ GAPs stimulate RHOQ GTPase activity (Rattus norvegicus)
RHOQ GAPs [cytosol] (Rattus norvegicus)
Srgap2 [cytosol] (Rattus norvegicus)
RHOU GTPase cycle (Rattus norvegicus)
RHOU binds effectors at the plasma membrane (Rattus norvegicus)
RHOU effectors [cytosol] (Rattus norvegicus)
Srgap2 [cytosol] (Rattus norvegicus)
RHOU:GTP:RHOU effectors [plasma membrane] (Rattus norvegicus)
RHOU effectors [cytosol] (Rattus norvegicus)
Srgap2 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:D4A208
Gene Names
Srgap2
Reference Genes
BioGPS Gene:360840 Srgap2
ENSEMBL:ENSRNOG00000006733
ENSEMBL:ENSRNOG00000006733.8 Srgap2
ENSEMBL:ENSRNOG00055020451
ENSEMBL:ENSRNOG00060014960
ENSEMBL:ENSRNOG00065019261
Monarch:360840 Srgap2
NCBI Gene:360840 Srgap2
UCSC:D4A208 Srgap2
Reference Transcript
RefSeq:XM_006249782.3 Srgap2
RefSeq:XM_006249783.3 Srgap2
Other Identifiers
10767539
1374754_at
1381126_at
1381814_at
1392134_x_at
17684076
360840
5662933
5669857
5752680
5767140
5824583
5825917
5948795
5979950
5996911
6004742
6049521
6108607
6169647
6211256
6229274
6247013
6281713
6312320
6332281
6332358
6362345
6367614
6460605
6478339
6499972
6519378
6694770
A_44_P109848
A_44_P203620
A_44_P761386
A_64_P015158
GE1241511
GE18657
GO:0005096
GO:0005515
GO:0005829
GO:0005886
GO:0007010
GO:0007165
GO:0014069
GO:0021816
GO:0023052
GO:0030154
GO:0030334
GO:0031267
GO:0031410
GO:0034330
GO:0042803
GO:0043197
GO:0043226
GO:0045211
GO:0045335
GO:0046847
GO:0048812
GO:0048856
GO:0048870
GO:0060996
GO:0098772
GO:1904861
GO:1904862
ILMN_1365139
rc_AA997441_at
rc_AI044216_at
Participates
as a candidate of
RHOQ GAPs [cytosol] (Rattus norvegicus)
CDC42 GAPs [cytosol] (Rattus norvegicus)
RHOF GAPs [cytosol] (Rattus norvegicus)
RHOU effectors [cytosol] (Rattus norvegicus)
as a member of
RAC1 GAPs [cytosol] (Rattus norvegicus)
as an output of
SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments (Rattus norvegicus)
as an input of
SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin (Rattus norvegicus)
as a component of
SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Rattus norvegicus)
Inferred From
SRGAP2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_006249844.1
,
XP_006249845.1
Ensembl
ENSRNOT00000085967
,
ENSRNOP00000068925
,
ENSRNOG00000006733
PRO
D4A208
RGD
1566016
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text