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ALK [plasma membrane]
Stable Identifier
R-RNO-201502
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
plasma membrane
Synonyms
F1LRZ0
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by ALK (Rattus norvegicus)
ALK autophosphorylation (Rattus norvegicus)
ALK [plasma membrane] (Rattus norvegicus)
ALK dimer:ligand:type I ALK binding TKI [plasma membrane] (Rattus norvegicus)
ligand-bound ALK dimer [plasma membrane] (Rattus norvegicus)
ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALK [plasma membrane] (Rattus norvegicus)
MDK:ALK dimer [plasma membrane] (Rattus norvegicus)
ALK homodimer [plasma membrane] (Rattus norvegicus)
ALK [plasma membrane] (Rattus norvegicus)
PTN:ALK dimer [plasma membrane] (Rattus norvegicus)
ALK homodimer [plasma membrane] (Rattus norvegicus)
ALK [plasma membrane] (Rattus norvegicus)
ligand-bound ALK dimer [plasma membrane] (Rattus norvegicus)
ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALK [plasma membrane] (Rattus norvegicus)
MDK:ALK dimer [plasma membrane] (Rattus norvegicus)
ALK homodimer [plasma membrane] (Rattus norvegicus)
ALK [plasma membrane] (Rattus norvegicus)
PTN:ALK dimer [plasma membrane] (Rattus norvegicus)
ALK homodimer [plasma membrane] (Rattus norvegicus)
ALK [plasma membrane] (Rattus norvegicus)
ALK binds ALKAL ligand (Rattus norvegicus)
ALK [plasma membrane] (Rattus norvegicus)
ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALK [plasma membrane] (Rattus norvegicus)
Active ALK phosphorylates IRS1 (Rattus norvegicus)
ALK [plasma membrane] (Rattus norvegicus)
Active ALK phosphorylates JAK3 (Rattus norvegicus)
ALK [plasma membrane] (Rattus norvegicus)
Active ALK phosphorylates PLCG1 (Rattus norvegicus)
ALK [plasma membrane] (Rattus norvegicus)
Active ALK phosphorylates SHC1 (Rattus norvegicus)
ALK [plasma membrane] (Rattus norvegicus)
Liganded-ALK dimer binds type I ALK-binding TKIs (Rattus norvegicus)
ALK dimer:ligand:type I ALK binding TKI [plasma membrane] (Rattus norvegicus)
ligand-bound ALK dimer [plasma membrane] (Rattus norvegicus)
ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALK [plasma membrane] (Rattus norvegicus)
MDK:ALK dimer [plasma membrane] (Rattus norvegicus)
ALK homodimer [plasma membrane] (Rattus norvegicus)
ALK [plasma membrane] (Rattus norvegicus)
PTN:ALK dimer [plasma membrane] (Rattus norvegicus)
ALK homodimer [plasma membrane] (Rattus norvegicus)
ALK [plasma membrane] (Rattus norvegicus)
ligand-bound ALK dimer [plasma membrane] (Rattus norvegicus)
ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALK [plasma membrane] (Rattus norvegicus)
MDK:ALK dimer [plasma membrane] (Rattus norvegicus)
ALK homodimer [plasma membrane] (Rattus norvegicus)
ALK [plasma membrane] (Rattus norvegicus)
PTN:ALK dimer [plasma membrane] (Rattus norvegicus)
ALK homodimer [plasma membrane] (Rattus norvegicus)
ALK [plasma membrane] (Rattus norvegicus)
MDK and PTN in ALK signaling (Rattus norvegicus)
ALK binds ligand midkine (MDK) (Rattus norvegicus)
ALK [plasma membrane] (Rattus norvegicus)
MDK:ALK [plasma membrane] (Rattus norvegicus)
ALK [plasma membrane] (Rattus norvegicus)
ALK binds ligand pleiotrophin (PTN) (Rattus norvegicus)
ALK [plasma membrane] (Rattus norvegicus)
PTN:ALK [plasma membrane] (Rattus norvegicus)
ALK [plasma membrane] (Rattus norvegicus)
PTPRZ dephosphorylates ligand-bound ALK dimers (Rattus norvegicus)
(PTN,MDK):ALK dimer [plasma membrane] (Rattus norvegicus)
MDK:ALK dimer [plasma membrane] (Rattus norvegicus)
ALK homodimer [plasma membrane] (Rattus norvegicus)
ALK [plasma membrane] (Rattus norvegicus)
PTN:ALK dimer [plasma membrane] (Rattus norvegicus)
ALK homodimer [plasma membrane] (Rattus norvegicus)
ALK [plasma membrane] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:F1LRZ0
Reference Genes
BioGPS Gene:266802
ENSEMBL:ENSRNOG00000008683
ENSEMBL:ENSRNOG00000008683.8
KEGG Gene (Rattus norvegicus):266802
Monarch:266802
NCBI Gene:266802
Reference Transcript
RefSeq:NM_001169101.2
Other Identifiers
10883025
1382541_at
17814154
266802
5649604
5654104
5673857
5741645
5742832
5841238
5853674
5866171
5968552
6069188
6104605
6184674
6193082
6195449
6207797
6305708
6328942
6352175
6429415
6445412
6457963
6496758
6506446
6513398
6517859
6567240
6589462
6595562
6645597
6696565
6701514
6723554
6724495
6740096
6740816
A_44_P508248
GE1126671
GO:0003824
GO:0004672
GO:0004713
GO:0004714
GO:0005524
GO:0005886
GO:0006468
GO:0006629
GO:0007169
GO:0007420
GO:0008201
GO:0016020
GO:0016310
GO:0016740
GO:0021766
GO:0023052
GO:0030154
GO:0030298
GO:0030534
GO:0032991
GO:0036211
GO:0036269
GO:0042127
GO:0042802
GO:0048856
GO:0050995
GO:0060089
GO:0060159
GO:0090648
GO:0097009
GO:0098772
GO:0140096
GO:1900006
ILMN_1353353
PH_rn_0014282
PH_rn_0019435
Participates
as an input of
ALK binds ligand pleiotrophin (PTN) (Rattus norvegicus)
ALK binds ligand midkine (MDK) (Rattus norvegicus)
ALK binds ALKAL ligand (Rattus norvegicus)
as a component of
PTN:ALK [plasma membrane] (Rattus norvegicus)
MDK:ALK [plasma membrane] (Rattus norvegicus)
ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Rattus norvegicus)
ALK homodimer [plasma membrane] (Rattus norvegicus)
Other forms of this molecule
phospho-p-7Y-ALK [plasma membrane]
Inferred From
ALK [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_001162572.1
Ensembl
ENSRNOT00000011630
,
ENSRNOG00000008683
,
ENSRNOP00000011630
RGD
628622
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