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Bcar1 [cytosol]
Stable Identifier
R-RNO-201625
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
BCAR1, Q63767
Locations in the PathwayBrowser
Expand all
Hemostasis (Rattus norvegicus)
Platelet activation, signaling and aggregation (Rattus norvegicus)
Platelet Aggregation (Plug Formation) (Rattus norvegicus)
Integrin signaling (Rattus norvegicus)
p130Cas linkage to MAPK signaling for integrins (Rattus norvegicus)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Rattus norvegicus)
BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Rattus norvegicus)
Bcar1 [cytosol] (Rattus norvegicus)
Recruitment of BCAR1 to PTK2 complex (Rattus norvegicus)
BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Rattus norvegicus)
Bcar1 [cytosol] (Rattus norvegicus)
Bcar1 [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Integrin signaling (Rattus norvegicus)
p130Cas linkage to MAPK signaling for integrins (Rattus norvegicus)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Rattus norvegicus)
BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Rattus norvegicus)
Bcar1 [cytosol] (Rattus norvegicus)
Recruitment of BCAR1 to PTK2 complex (Rattus norvegicus)
BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Rattus norvegicus)
Bcar1 [cytosol] (Rattus norvegicus)
Bcar1 [cytosol] (Rattus norvegicus)
Signaling by Non-Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by PTK6 (Rattus norvegicus)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Rattus norvegicus)
PTK6 binds BCAR1 (Rattus norvegicus)
Bcar1 [cytosol] (Rattus norvegicus)
p-Y342-PTK6:BCAR1 [cytosol] (Rattus norvegicus)
Bcar1 [cytosol] (Rattus norvegicus)
PTK6 phosphorylates BCAR1 (Rattus norvegicus)
p-Y342-PTK6:BCAR1 [cytosol] (Rattus norvegicus)
Bcar1 [cytosol] (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by PDGF (Rattus norvegicus)
Downstream signal transduction (Rattus norvegicus)
p130Cas and C3G bind PDGFR bound Crk (Rattus norvegicus)
Bcar1 [cytosol] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:Crk:p130Cas:C3G [plasma membrane] (Rattus norvegicus)
Bcar1 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:Q63767
Gene Names
Bcar1
Reference Genes
BioGPS Gene:25414 Bcar1
ENSEMBL:ENSRNOG00000019253
KEGG Gene (Rattus norvegicus):25414 Bcar1
Monarch:25414 Bcar1
NCBI Gene:25414 Bcar1
UCSC:Q63767 Bcar1
Reference Transcript
RefSeq:NM_012931.1 Bcar1
Participates
as an input of
Recruitment of BCAR1 to PTK2 complex (Rattus norvegicus)
p130Cas and C3G bind PDGFR bound Crk (Rattus norvegicus)
PTK6 binds BCAR1 (Rattus norvegicus)
as a component of
BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:Crk:p130Cas:C3G [plasma membrane] (Rattus norvegicus)
p-Y342-PTK6:BCAR1 [cytosol] (Rattus norvegicus)
Other forms of this molecule
phospho-Bcar1 [cytosol]
phospho-Bcar1 [cytosol]
phospho-Bcar1 [cytosol]
Inferred From
BCAR1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_037063.1
PRO
Q63767
RGD
2406
PDB
1X27
,
1Z23
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P18031 PTPN1
2
PTPN1 [cytosol]
(R-HSA-210625)
PTPN1 [endosome membrane]
(R-HSA-9815895)
0.591
5
UniProt:Q9WUD9 Src
10
MyrG,p-Y419-Src [plasma membrane]
(R-RNO-9037057)
phospho-p-Y419-SRC [cytosol]
(R-RNO-8964276)
SRC [cytosol]
(R-RNO-9628701)
MyrG-SRC [plasma membrane]
(R-RNO-8876922)
phospho-p-Y419-SRC-1 [plasma membrane]
(R-RNO-112331)
SRC_RAT [cytosol]
(R-RNO-548926)
MyrG-p-Y419-Src [plasma membrane]
(R-RNO-8937901)
phospho-MyrG,p-Y530-SRC [plasma membrane]
(R-RNO-377598)
phospho-p-Y419-SRC [cytosol]
(R-RNO-377592)
SRC-1 [plasma membrane]
(R-RNO-65043)
0.558
2
UniProt:P06240 Lck
5
phospho-p-Y394-LCK [plasma membrane]
(R-MMU-8857940)
Lck [cytosol]
(R-MMU-539041)
phospho-p-Y505-LCK [plasma membrane]
(R-MMU-202159)
phospho-p-Y394-LCK [cytosol]
(R-MMU-202308)
LCK [cytosol]
(R-MMU-167609)
0.558
2
UniProt:P06239 LCK
4
p-Y394-LCK [plasma membrane]
(R-HSA-8857940)
p-Y505-LCK [plasma membrane]
(R-HSA-202159)
p-Y394-LCK [cytosol]
(R-HSA-202308)
LCK [cytosol]
(R-HSA-167609)
0.532
3
UniProt:P63104 YWHAZ
2
YWHAZ [nucleoplasm]
(R-HSA-450469)
YWHAZ [cytosol]
(R-HSA-206099)
0.527
2
UniProt:P05480 Src
13
SRC-2 [cytosol]
(R-MMU-191648)
phospho-MyrG-p-Y419-SRC [plasma membrane]
(R-MMU-1810408)
phospho-MyrG,p-Y530-SRC [plasma membrane]
(R-MMU-377598)
phospho-p-Y419-SRC [cytosol]
(R-MMU-377592)
SRC-1 [plasma membrane]
(R-MMU-65043)
Src [cytosol]
(R-MMU-418782)
phospho-p-Y419-SRC-1 [plasma membrane]
(R-MMU-112331)
MyrG-SRC [plasma membrane]
(R-MMU-8876922)
Activated Src [nucleoplasm]
(R-MMU-8937700)
SRC [cytosol]
(R-MMU-9628701)
phospho-p-Y419-SRC [cytosol]
(R-MMU-8964276)
MyrG-p-Y424-Src [plasma membrane]
(R-MMU-9011258)
p-Y416-Src [cytosol]
(R-MMU-8964306)
0.471
2
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