Reactome | DUSP7 [nucleoplasm]

DUSP7 [nucleoplasm]

Stable Identifier

R-RNO-203791

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

Q63340

Locations in the PathwayBrowser

Expand all

Immune System (Rattus norvegicus)

- Cytokine Signaling in Immune system (Rattus norvegicus)
  - Signaling by Interleukins (Rattus norvegicus)
    - Interleukin-17 signaling (Rattus norvegicus)
      - MAP kinase activation (Rattus norvegicus)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Rattus norvegicus)
        
        ERK/MAPK targets (Rattus norvegicus)
        
        ERKs are inactivated (Rattus norvegicus)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Rattus norvegicus)
        
        ERK-specific DUSP [nucleoplasm] (Rattus norvegicus)
        
        DUSP7 [nucleoplasm] (Rattus norvegicus)
- Innate Immune System (Rattus norvegicus)
  - Toll-like Receptor Cascades (Rattus norvegicus)
    - Toll Like Receptor 10 (TLR10) Cascade (Rattus norvegicus)
      - MyD88 cascade initiated on plasma membrane (Rattus norvegicus)
        
        MAP kinase activation (Rattus norvegicus)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Rattus norvegicus)
        
        ERK/MAPK targets (Rattus norvegicus)
        
        ERKs are inactivated (Rattus norvegicus)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Rattus norvegicus)
        
        ERK-specific DUSP [nucleoplasm] (Rattus norvegicus)
        
        DUSP7 [nucleoplasm] (Rattus norvegicus)
    - Toll Like Receptor 2 (TLR2) Cascade (Rattus norvegicus)
      - Toll Like Receptor TLR1:TLR2 Cascade (Rattus norvegicus)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
        
        MAP kinase activation (Rattus norvegicus)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Rattus norvegicus)
        
        ERK/MAPK targets (Rattus norvegicus)
        
        ERKs are inactivated (Rattus norvegicus)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Rattus norvegicus)
        
        ERK-specific DUSP [nucleoplasm] (Rattus norvegicus)
        
        DUSP7 [nucleoplasm] (Rattus norvegicus)
      - Toll Like Receptor TLR6:TLR2 Cascade (Rattus norvegicus)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
        
        MAP kinase activation (Rattus norvegicus)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Rattus norvegicus)
        
        ERK/MAPK targets (Rattus norvegicus)
        
        ERKs are inactivated (Rattus norvegicus)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Rattus norvegicus)
        
        ERK-specific DUSP [nucleoplasm] (Rattus norvegicus)
        
        DUSP7 [nucleoplasm] (Rattus norvegicus)
    - Toll Like Receptor 3 (TLR3) Cascade (Rattus norvegicus)
      - MAP kinase activation (Rattus norvegicus)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Rattus norvegicus)
        
        ERK/MAPK targets (Rattus norvegicus)
        
        ERKs are inactivated (Rattus norvegicus)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Rattus norvegicus)
        
        ERK-specific DUSP [nucleoplasm] (Rattus norvegicus)
        
        DUSP7 [nucleoplasm] (Rattus norvegicus)
    - Toll Like Receptor 4 (TLR4) Cascade (Rattus norvegicus)
      - MyD88-independent TLR4 cascade (Rattus norvegicus)
        
        TRIF (TICAM1)-mediated TLR4 signaling (Rattus norvegicus)
        
        MAP kinase activation (Rattus norvegicus)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Rattus norvegicus)
        
        ERK/MAPK targets (Rattus norvegicus)
        
        ERKs are inactivated (Rattus norvegicus)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Rattus norvegicus)
        
        ERK-specific DUSP [nucleoplasm] (Rattus norvegicus)
        
        DUSP7 [nucleoplasm] (Rattus norvegicus)
      - MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
        
        MAP kinase activation (Rattus norvegicus)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Rattus norvegicus)
        
        ERK/MAPK targets (Rattus norvegicus)
        
        ERKs are inactivated (Rattus norvegicus)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Rattus norvegicus)
        
        ERK-specific DUSP [nucleoplasm] (Rattus norvegicus)
        
        DUSP7 [nucleoplasm] (Rattus norvegicus)
    - Toll Like Receptor 5 (TLR5) Cascade (Rattus norvegicus)
      - MyD88 cascade initiated on plasma membrane (Rattus norvegicus)
        
        MAP kinase activation (Rattus norvegicus)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Rattus norvegicus)
        
        ERK/MAPK targets (Rattus norvegicus)
        
        ERKs are inactivated (Rattus norvegicus)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Rattus norvegicus)
        
        ERK-specific DUSP [nucleoplasm] (Rattus norvegicus)
        
        DUSP7 [nucleoplasm] (Rattus norvegicus)
    - Toll Like Receptor 7/8 (TLR7/8) Cascade (Rattus norvegicus)
      - MyD88 dependent cascade initiated on endosome (Rattus norvegicus)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Rattus norvegicus)
        
        MAP kinase activation (Rattus norvegicus)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Rattus norvegicus)
        
        ERK/MAPK targets (Rattus norvegicus)
        
        ERKs are inactivated (Rattus norvegicus)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Rattus norvegicus)
        
        ERK-specific DUSP [nucleoplasm] (Rattus norvegicus)
        
        DUSP7 [nucleoplasm] (Rattus norvegicus)
    - Toll Like Receptor 9 (TLR9) Cascade (Rattus norvegicus)
      - MyD88 dependent cascade initiated on endosome (Rattus norvegicus)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Rattus norvegicus)
        
        MAP kinase activation (Rattus norvegicus)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Rattus norvegicus)
        
        ERK/MAPK targets (Rattus norvegicus)
        
        ERKs are inactivated (Rattus norvegicus)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Rattus norvegicus)
        
        ERK-specific DUSP [nucleoplasm] (Rattus norvegicus)
        
        DUSP7 [nucleoplasm] (Rattus norvegicus)

Signal Transduction (Rattus norvegicus)

- Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
  - Signaling by NTRKs (Rattus norvegicus)
    - Signaling by NTRK1 (TRKA) (Rattus norvegicus)
      - Nuclear Events (kinase and transcription factor activation) (Rattus norvegicus)
        
        ERK/MAPK targets (Rattus norvegicus)
        
        ERKs are inactivated (Rattus norvegicus)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Rattus norvegicus)
        
        ERK-specific DUSP [nucleoplasm] (Rattus norvegicus)
        
        DUSP7 [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:Q63340

Reference Genes

BioGPS Gene:300980

ENSEMBL:ENSRNOG00000010789

ENSEMBL:ENSRNOG00000010789.8

KEGG Gene (Rattus norvegicus):300980

Monarch:300980

NCBI Gene:300980

UCSC:Q63340

Reference Transcript

RefSeq:NM_001100547.1

Other Identifiers

10912837

1377992_at

1379009_at

17847293

300980

5808376

6101080

6123603

6187671

6383327

A_44_P463702

A_64_P020350

GE1138418

GE1154167

GO:0003824

GO:0005829

GO:0006470

GO:0008138

GO:0016311

GO:0016787

GO:0016791

GO:0017017

GO:0036211

GO:0140096

ILMN_1370892

ILMN_1530333

PH_rn_0002293

X94186_at

Participates

as a member of

ERK-specific DUSP [nucleoplasm] (Rattus norvegicus)

Other forms of this molecule

DUSP7 [cytosol]

Inferred From

DUSP7 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001094017.1

IntEnz

3.1.3.16

Ensembl

ENSRNOP00000014770, ENSRNOT00000014770, ENSRNOG00000010789

PRO

Q63340

RGD

735026

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