Reactome | Cacnb3 [cytosol]

Cacnb3 [cytosol]

Stable Identifier

R-RNO-210401

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

CACNB3, P54287

Locations in the PathwayBrowser

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Metabolism (Rattus norvegicus)

- Integration of energy metabolism (Rattus norvegicus)
  - Regulation of insulin secretion (Rattus norvegicus)
    - Calcium Influx through Voltage-gated Calcium Channels (Rattus norvegicus)
      - Voltage-gated Calcium Channels (pancreatic beta cell) [plasma membrane] (Rattus norvegicus)
        
        Voltage-gated Calcium Channel, L-type 1.2 [plasma membrane] (Rattus norvegicus)
        
        Beta Subunit of Voltage-dependent Calcium Channel (pancreatic beta cell) [cytosol] (Rattus norvegicus)
        
        Cacnb3 [cytosol] (Rattus norvegicus)
        
        Voltage-gated Calcium Channel, L-type, 1.3 [plasma membrane] (Rattus norvegicus)
        
        Beta Subunit of Voltage-dependent Calcium Channel (pancreatic beta cell) [cytosol] (Rattus norvegicus)
        
        Cacnb3 [cytosol] (Rattus norvegicus)
        
        Voltage-gated Calcium Channel, P,Q-type 2.1 [plasma membrane] (Rattus norvegicus)
        
        Beta Subunit of Voltage-dependent Calcium Channel (pancreatic beta cell) [cytosol] (Rattus norvegicus)
        
        Cacnb3 [cytosol] (Rattus norvegicus)
        
        Voltage-gated Calcium Channel, R-type 2.3 [plasma membrane] (Rattus norvegicus)
        
        Beta Subunit of Voltage-dependent Calcium Channel (pancreatic beta cell) [cytosol] (Rattus norvegicus)
        
        Cacnb3 [cytosol] (Rattus norvegicus)

Neuronal System (Rattus norvegicus)

- Transmission across Chemical Synapses (Rattus norvegicus)
  - Presynaptic depolarization and calcium channel opening (Rattus norvegicus)
    - Ca2+ influx through voltage gated Ca2+ channels (Rattus norvegicus)
      - Voltage Gated Ca2+ Channel [plasma membrane] (Rattus norvegicus)
        
        calcium channel multimer of N type VGCC [plasma membrane] (Rattus norvegicus)
        
        Cacnb3 [cytosol] (Rattus norvegicus)
        
        calcium channel multimer of R type VGCC [plasma membrane] (Rattus norvegicus)
        
        beta subunit of VGCC [cytosol] (Rattus norvegicus)
        
        Cacnb3 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P54287 Cacnb3

Gene Names

Cacnb3, Cacnlb3

Chain

chain:1-484

Reference Genes

BioGPS Gene:25297 Cacnb3

ENSEMBL:ENSRNOG00000054274.2 Cacnb3

ENSEMBL:ENSRNOG00055025822 Cacnb3

ENSEMBL:ENSRNOG00060008268 Cacnb3

ENSEMBL:ENSRNOG00065024413 Cacnb3

KEGG Gene (Rattus norvegicus):25297 Cacnb3

Monarch:25297 Cacnb3

NCBI Gene:25297 Cacnb3

UCSC:P54287 Cacnb3

Reference Transcript

RefSeq:NM_012828.2 Cacnb3

Other Identifiers

10899023

1387042_at

17832085

25297

5640037

5783015

5835826

5876055

5885083

5918382

5973784

5984454

6132374

6172228

6277811

6453317

6478251

6665309

6668964

A_44_P245314

GE19992

GO:0005215

GO:0005245

GO:0005515

GO:0005886

GO:0005891

GO:0055085

GO:0070588

ILMN_1354834

M88751_at

PH_rn_0011503

Participates

as a candidate of

as a component of

calcium channel multimer of N type VGCC [plasma membrane] (Rattus norvegicus)

Other forms of this molecule

Voltage-dependent L-type calcium channel subunit beta-3 [plasma membrane]

Inferred From

CACNB3 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_036960.1

Ensembl

ENSRNOG00000054274, ENSRNOT00000081206, ENSRNOP00000073026

PRO

P54287

RGD

2248

PDB

1VYU, 1VYT

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P55040 GEM	1	GEM [plasma membrane] (R-HSA-9769962)	0.499	2