GSSeSG is reduced to GSSeH and GSH by Gsr

Stable Identifier
R-RNO-2408514
Type
Reaction [transition]
Species
Rattus norvegicus
Compartment
General
SVG |   | PPTX  | SBGN
GSSeSG is reduced to GSSeH and GSH by Gsr

In the rat cytosol, glutathione reductase (Gsr) homodimer is involved in the reduction of selenodiglutathione (GSSeSG) into gluthathioselenol (GSSeH) and reduced glutathione (GSH) (Bjornstedt et al. 1992).

Literature References
PubMed ID Title Journal Year
1569062 Selenodiglutathione is a highly efficient oxidant of reduced thioredoxin and a substrate for mammalian thioredoxin reductase

Björnstedt, M, Kumar, S, Holmgren, A

J. Biol. Chem. 1992
Participants
Catalyst Activity
Catalyst Activity
Title
selenodiglutathione-disulfide reductase activity of 2xGsr-2:2xFAD [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created