Reactome | Dnajc6 [cytosol]

Dnajc6 [cytosol]

Stable Identifier

R-RNO-264472

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

DNAJC6, A0A8I6AMT9

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Rattus norvegicus)

- Membrane Trafficking (Rattus norvegicus)
  - Clathrin-mediated endocytosis (Rattus norvegicus)
    - Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        GAK,DNAJC6 [cytosol] (Rattus norvegicus)
        
        Dnajc6 [cytosol] (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        GAK,DNAJC6 [cytosol] (Rattus norvegicus)
        
        Dnajc6 [cytosol] (Rattus norvegicus)
    - Clathrin recruits auxilins to the clathrin-coated vesicle (Rattus norvegicus)
      - GAK,DNAJC6 [cytosol] (Rattus norvegicus)
        
        Dnajc6 [cytosol] (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        GAK,DNAJC6 [cytosol] (Rattus norvegicus)
        
        Dnajc6 [cytosol] (Rattus norvegicus)
    - Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        GAK,DNAJC6 [cytosol] (Rattus norvegicus)
        
        Dnajc6 [cytosol] (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        GAK,DNAJC6 [cytosol] (Rattus norvegicus)
        
        Dnajc6 [cytosol] (Rattus norvegicus)
    - HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        GAK,DNAJC6 [cytosol] (Rattus norvegicus)
        
        Dnajc6 [cytosol] (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        GAK,DNAJC6 [cytosol] (Rattus norvegicus)
        
        Dnajc6 [cytosol] (Rattus norvegicus)
    - RAB5 and GAPVD1 bind AP-2 (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        GAK,DNAJC6 [cytosol] (Rattus norvegicus)
        
        Dnajc6 [cytosol] (Rattus norvegicus)
  - trans-Golgi Network Vesicle Budding (Rattus norvegicus)
    - Golgi Associated Vesicle Biogenesis (Rattus norvegicus)
      - trans-Golgi Network Derived Vesicle Uncoating (Rattus norvegicus)
        
        HSC70:Auxillin Complex [cytosol] (Rattus norvegicus)
        
        Dnajc6 [cytosol] (Rattus norvegicus)
    - Lysosome Vesicle Biogenesis (Rattus norvegicus)
      - trans-Golgi Network Derived Lysosomal Vesicle Uncoating (Rattus norvegicus)
        
        HSC70:Auxillin Complex [cytosol] (Rattus norvegicus)
        
        Dnajc6 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:A0A8I6AMT9

Gene Names

Dnajc6

Reference Genes

ENSEMBL:ENSRNOG00000052887

ENSEMBL:ENSRNOG00000052887.2 Dnajc6

Reference Transcript

RefSeq:XM_006238446.3 Dnajc6

Other Identifiers

10870269

1377125_at

1386648_at

17800183

313409

5642443

5785319

5875029

5884171

6027539

6067712

6117124

6133949

6234461

6277659

6332505

6392430

6435290

6440052

6444754

6471347

6478272

6488301

6506048

6531369

6536459

6596070

6608023

6620059

6631979

6698860

6719443

A_42_P536403

A_44_P520725

A_44_P905187

GE1131831

GO:0003824

GO:0005886

GO:0014069

GO:0016191

GO:0016192

GO:0016311

GO:0016787

GO:0016791

GO:0043226

GO:0045202

GO:0072318

GO:0098894

GO:2000369

ILMN_1369280

PH_rn_0012664

PH_rn_0020298

rc_AI228654_at

Participates

as a member of

GAK,DNAJC6 [cytosol] (Rattus norvegicus)

as a component of

HSC70:Auxillin Complex [cytosol] (Rattus norvegicus)

Inferred From

DNAJC6 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_006238508.1

Ensembl

ENSRNOG00000052887, ENSRNOP00000095523, ENSRNOT00000113921

RGD

1309900

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