Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
Ntrk1 [plasma membrane]
Stable Identifier
R-RNO-3008784
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
plasma membrane
Synonyms
NTRK1, P35739
Locations in the PathwayBrowser for interactor UniProt:P62994
Expand all
Signal Transduction (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by NTRKs (Rattus norvegicus)
Signaling by NTRK1 (TRKA) (Rattus norvegicus)
Activation of TRKA receptors (Rattus norvegicus)
TRKA activation by NGF (Rattus norvegicus)
The bound receptor dimerizes (Rattus norvegicus)
Ntrk1 [plasma membrane] (Rattus norvegicus)
beta-NGF dimer binds to TrkA receptor (Rattus norvegicus)
Ntrk1 [plasma membrane] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P35739 Ntrk1
Gene Names
Ntrk1, Trk, Trka
Chain
signal peptide:1-32, chain:33-799
Reference Genes
BioGPS Gene:59109 Ntrk1
ENSEMBL:ENSRNOG00000013953 Ntrk1
KEGG Gene (Rattus norvegicus):59109 Ntrk1
Monarch:59109 Ntrk1
NCBI Gene:59109 Ntrk1
UCSC:P35739 Ntrk1
Reference Transcript
RefSeq:NM_021589.1 Ntrk1
Other Identifiers
10824188
1369000_at
17748555
5645907
5823701
5835472
59109
6015104
6045832
6063660
6155166
6290771
6306265
6353766
6369415
6400183
6479369
6519504
6538508
6539034
6610541
6614150
6620970
6676650
6716900
A_42_P780039
A_64_P115417
GE20747
GO:0000003
GO:0000139
GO:0000166
GO:0000902
GO:0001934
GO:0002376
GO:0003674
GO:0004672
GO:0004675
GO:0004713
GO:0004714
GO:0005004
GO:0005030
GO:0005166
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005737
GO:0005768
GO:0005769
GO:0005770
GO:0005794
GO:0005886
GO:0005887
GO:0006464
GO:0006468
GO:0006950
GO:0007165
GO:0007169
GO:0007178
GO:0007267
GO:0007275
GO:0007399
GO:0007411
GO:0007568
GO:0007611
GO:0007623
GO:0008150
GO:0008219
GO:0008283
GO:0008285
GO:0009058
GO:0009314
GO:0009986
GO:0010465
GO:0010623
GO:0010976
GO:0014068
GO:0016020
GO:0016021
GO:0016301
GO:0016310
GO:0016740
GO:0018108
GO:0019233
GO:0019899
GO:0019900
GO:0021553
GO:0022607
GO:0030154
GO:0030183
GO:0030424
GO:0030425
GO:0031175
GO:0031410
GO:0031667
GO:0031901
GO:0031902
GO:0032991
GO:0033674
GO:0034330
GO:0034641
GO:0035094
GO:0038083
GO:0038180
GO:0040011
GO:0042490
GO:0042493
GO:0042802
GO:0042803
GO:0043025
GO:0043068
GO:0043121
GO:0043167
GO:0043226
GO:0043235
GO:0043408
GO:0043410
GO:0043524
GO:0043547
GO:0045766
GO:0046579
GO:0046777
GO:0048011
GO:0048013
GO:0048406
GO:0048485
GO:0048646
GO:0048666
GO:0048678
GO:0048856
GO:0050877
GO:0050965
GO:0050966
GO:0051092
GO:0051599
GO:0051602
GO:0051896
GO:0051965
GO:0051968
GO:0055037
GO:0055038
GO:0060009
GO:0060384
GO:0060385
GO:0061368
GO:0070374
GO:0071316
GO:0071363
GO:1901215
GO:1990090
ILMN_1370831
M85214_at
PH_rn_0011613
Participant Of
input
beta-NGF dimer binds to TrkA receptor
The bound receptor dimerizes
hasComponent
beta-NGF dimer:TrkA receptor [plasma membrane]
beta-NGF dimer:TrkA receptor dimer [plasma membrane]
Other forms of this molecule
Phosphorylated TrkA receptor [Golgi membrane]
Ntrk1 [Golgi membrane]
TrkA receptor [plasma membrane]
Phosphorylated TrkA receptor [plasma membrane]
phospho-Ntrk1 [endosome membrane]
phospho-Ntrk1 [plasma membrane]
Inferred From
NTRK1 [plasma membrane] (Homo sapiens)
Cross References
RefSeq
NP_067600.1
IntEnz
2.7.10.1
Ensembl
ENSRNOP00000018961
,
ENSRNOG00000013953
,
ENSRNOT00000018961
PRO
P35739
RGD
620144
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P62994 Grb2
3
Grb2 [plasma membrane]
(R-RNO-202993)
Grb2 [cytosol]
(R-RNO-55929)
Grb2 [cytosol]
(R-RNO-74686)
0.548
6
ChEBI:62935 DHEA-7-CMO
0.544
5
UniProt:P27671
1
Rasgrf1 [plasma membrane]
(R-MMU-442723)
0.524
3
UniProt:P08592
9
App [cytosol]
(R-RNO-9617603)
App [trans-Golgi network membrane]
(R-RNO-5229136)
App [endosome lumen]
(R-RNO-5229077)
App [extracellular region]
(R-RNO-49335)
App [platelet alpha granule lumen]
(R-RNO-139835)
phospho-App [endoplasmic reticulum lumen]
(R-RNO-8957012)
App [endoplasmic reticulum lumen]
(R-RNO-8956696)
App [extracellular region]
(R-RNO-976740)
App [extracellular region]
(R-RNO-879340)
0.463
2
© 2021
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text