Reactome | PRMT1 [nucleoplasm]

PRMT1 [nucleoplasm]

Stable Identifier

R-RNO-3215140

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

Q63009

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Rattus norvegicus)

- RNA Polymerase II Transcription (Rattus norvegicus)
  - Generic Transcription Pathway (Rattus norvegicus)
    - Transcriptional regulation by RUNX1 (Rattus norvegicus)
      - RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Rattus norvegicus)
        
        Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Rattus norvegicus)
        
        H3K4me2-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        MeR206,MeR210-RUNX1:CBFB:PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        H3K4me3-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        MeR206,MeR210-RUNX1:CBFB:PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Rattus norvegicus)
        
        H3K4me2-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        MeR206,MeR210-RUNX1:CBFB:PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        H3K4me3-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        MeR206,MeR210-RUNX1:CBFB:PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Rattus norvegicus)
        
        H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        MeR206,MeR210-RUNX1:CBFB:PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        H3K4me3-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        MeR206,MeR210-RUNX1:CBFB:PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        MeR206,MeR210-RUNX1:CBFB:PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Rattus norvegicus)
        
        H3K4me2-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        MeR206,MeR210-RUNX1:CBFB:PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        H3K4me3-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        MeR206,MeR210-RUNX1:CBFB:PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        PRMT1 arginine-methylates RUNX1 (Rattus norvegicus)
        
        MeR206,MeR210-RUNX1:CBFB:PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        RUNX1:CBFB:PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        RUNX1 binds PRMT1 (Rattus norvegicus)
        
        PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        RUNX1:CBFB:PRMT1 [nucleoplasm] (Rattus norvegicus)
        
        PRMT1 [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:Q63009

Reference Genes

BioGPS Gene:60421

ENSEMBL:ENSRNOG00000026109

ENSEMBL:ENSRNOG00055005632

ENSEMBL:ENSRNOG00060007875

ENSEMBL:ENSRNOG00065028078

KEGG Gene (Rattus norvegicus):60421

Monarch:60421

NCBI Gene:60421

UCSC:Q63009

Reference Transcript

RefSeq:NM_024363.1

Participates

as an input of

as a component of

Other forms of this molecule

PRMT1 [cytosol]

Inferred From

PRMT1,PRMT6 [nucleoplasm] (Homo sapiens)

PRMT1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_077339.1

ZINC target

Q63009

PRO

Q63009

RGD

62020

ZINC - Predictions - Purchasable

ANM1_RAT

PDB

1ORI, 3Q7E, 1OR8, 1ORH

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q63009	2	PRMT1 [nucleoplasm] (R-RNO-3215140) PRMT1 [cytosol] (R-RNO-9632173)	0.573	2
UniProt:P62633 CNBP	2	MeR25,27-CNBP [cytosol] (R-HSA-9759641) CNBP [cytosol] (R-HSA-9759645)	0.558	2
UniProt:Q9JIL3	3	phospho-Ilf3 [cytosol] (R-RNO-9836381) Ilf3 [cytosol] (R-RNO-450564) Ilf3 [nucleoplasm] (R-RNO-9760401)	0.508	2

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