Reactome | Cep72 [cytosol]

Cep72 [cytosol]

Stable Identifier

R-RNO-380321

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

CEP72, D3ZVQ1

Locations in the PathwayBrowser

Expand all

Organelle biogenesis and maintenance (Rattus norvegicus)

- Cilium Assembly (Rattus norvegicus)
  - Anchoring of the basal body to the plasma membrane (Rattus norvegicus)
    - C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Rattus norvegicus)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Cep72 [cytosol] (Rattus norvegicus)
      - mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Cep72 [cytosol] (Rattus norvegicus)
    - C2CD3 binds the mother centriole (Rattus norvegicus)
      - mother centriole [cytosol] (Rattus norvegicus)
        
        Cep72 [cytosol] (Rattus norvegicus)
      - mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Cep72 [cytosol] (Rattus norvegicus)
    - CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Rattus norvegicus)
      - basal body:transition zone proteins [cytosol] (Rattus norvegicus)
        
        basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        Cep72 [cytosol] (Rattus norvegicus)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Rattus norvegicus)
        
        basal body:transition zone proteins [cytosol] (Rattus norvegicus)
        
        basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        Cep72 [cytosol] (Rattus norvegicus)
    - CP110 and CEP97 dissociate from the centriole (Rattus norvegicus)
      - basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        Cep72 [cytosol] (Rattus norvegicus)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Cep72 [cytosol] (Rattus norvegicus)
    - MARK4 binds ODF2 in the centriole (Rattus norvegicus)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Cep72 [cytosol] (Rattus norvegicus)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Cep72 [cytosol] (Rattus norvegicus)
    - RAB3IP stimulates nucleotide exchange on RAB8A (Rattus norvegicus)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Rattus norvegicus)
        
        basal body:transition zone proteins [cytosol] (Rattus norvegicus)
        
        basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        Cep72 [cytosol] (Rattus norvegicus)
    - Recruitment of transition zone proteins (Rattus norvegicus)
      - basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        Cep72 [cytosol] (Rattus norvegicus)
      - basal body:transition zone proteins [cytosol] (Rattus norvegicus)
        
        basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        Cep72 [cytosol] (Rattus norvegicus)
    - The distal appendage proteins recruit TTBK2 (Rattus norvegicus)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Cep72 [cytosol] (Rattus norvegicus)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Cep72 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:D3ZVQ1

Gene Names

Cep72

Reference Genes

ENSEMBL:ENSRNOG00000015465

ENSEMBL:ENSRNOG00000015465.8 Cep72

UCSC:D3ZVQ1 Cep72

Reference Transcript

Other Identifiers

10702505

1395778_at

17611325

308064

5720020

5991034

6069301

6093967

6111836

6141883

6265757

6270202

6274253

6296539

6359333

6486421

6566497

6569742

6585767

6595384

6602557

6651334

6706638

A_44_P185771

A_44_P332834

A_64_P138959

GE1268818

GO:0005515

GO:0005813

GO:0005815

GO:0005829

GO:0005856

GO:0007010

GO:0007051

GO:0007099

GO:0033566

GO:0034451

GO:0043226

GO:1904779

ILMN_1367221

PH_rn_0018060

PH_rn_0022995

Participates

as a component of

Inferred From

CEP72 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_217737.4, XP_001056326.1

Ensembl

ENSRNOP00000020780, ENSRNOT00000020780, ENSRNOG00000015465

RGD

1566336

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