Reactome | Hcrtr2 [plasma membrane]

Hcrtr2 [plasma membrane]

Stable Identifier

R-RNO-389421

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

HCRTR2, P56719

Locations in the PathwayBrowser

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Signal Transduction (Rattus norvegicus)

- Signaling by GPCR (Rattus norvegicus)
  - GPCR downstream signalling (Rattus norvegicus)
    - G alpha (q) signalling events (Rattus norvegicus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Rattus norvegicus)
        
        HCRTR2:HCRT(70-97) [plasma membrane] (Rattus norvegicus)
        
        Hcrtr2 [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Rattus norvegicus)
        
        HCRTR2:HCRT(70-97) [plasma membrane] (Rattus norvegicus)
        
        Hcrtr2 [plasma membrane] (Rattus norvegicus)
  - GPCR ligand binding (Rattus norvegicus)
    - Class A/1 (Rhodopsin-like receptors) (Rattus norvegicus)
      - Peptide ligand-binding receptors (Rattus norvegicus)
        
        Orexin and neuropeptides FF and QRFP bind to their respective receptors (Rattus norvegicus)
        
        Orexin 2 receptor can bind orexin-B neuropeptide (Rattus norvegicus)
        
        HCRTR2:HCRT(70-97) [plasma membrane] (Rattus norvegicus)
        
        Hcrtr2 [plasma membrane] (Rattus norvegicus)
        
        Hcrtr2 [plasma membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P56719

Gene Names

Hcrtr2

Reference Genes

BioGPS Gene:25605 Hcrtr2

ENSEMBL:ENSRNOG00000011251

ENSEMBL:ENSRNOG00000011251.5 Hcrtr2

ENSEMBL:ENSRNOG00055007550

ENSEMBL:ENSRNOG00060018872

ENSEMBL:ENSRNOG00065017232

KEGG Gene (Rattus norvegicus):25605 Hcrtr2

Monarch:25605 Hcrtr2

NCBI Gene:25605 Hcrtr2

UCSC:P56719 Hcrtr2

Reference Transcript

RefSeq:NM_013074.1 Hcrtr2

Other Identifiers

10918761

1369377_at

17854064

25605

5713497

5752350

5765294

5785419

5921454

5934667

5979339

6056777

6132790

6503377

6602176

6648888

AF041246_at

A_44_P206844

GE20156

GO:0004930

GO:0005886

GO:0007186

GO:0007200

GO:0007218

GO:0007631

GO:0016020

GO:0016499

GO:0022410

GO:0023052

GO:0040011

GO:0051480

GO:0055065

GO:0060089

ILMN_1357940

PH_rn_0011544

Participates

as an input of

Orexin 2 receptor can bind orexin-B neuropeptide (Rattus norvegicus)

as a component of

HCRTR2:HCRT(70-97) [plasma membrane] (Rattus norvegicus)

Inferred From

HCRTR2 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_037206.1

ZINC - Substances

OX2R_RAT

ZINC target

P56719

Ensembl

ENSRNOG00000011251, ENSRNOT00000015824, ENSRNOP00000015824

PRO

P56719

RGD

2788

ZINC - Predictions - Purchasable

OX2R_RAT

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