NCAM1 cis-homophilic interaction

Stable Identifier
R-RNO-420387
Type
Reaction [binding]
Species
Rattus norvegicus
Compartment
ReviewStatus
5/5
General
SVG |   | PPTX  | SBGN
NCAM1 cis-homophilic interaction
NCAM1 located on the cell membrane can participate in parallel cis and antiparallel trans-homophilic interactions. The cis-interaction is mediated by reciprocal IgI-IgII interactions: the IgI domain of one NCAM1 molecule interacts with the IgII domain of a second.
Literature References
PubMed ID Title Journal Year
14527396 Structure and interactions of NCAM Ig1-2-3 suggest a novel zipper mechanism for homophilic adhesion

Kasper, C, Diederichs, K, Soroka, V, Welte, W, Poulsen, FM, Larsen, IK, Kiselyov, VV, Kastrup, JS, Kolkova, K, Berezin, V, Bock, E, Breed, J

Structure 2003
Participants
Orthologous Events
Authored
Reviewed
Created
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