Reactome | GRM6 [plasma membrane]

GRM6 [plasma membrane]

Stable Identifier

R-RNO-420574

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

P35349

Locations in the PathwayBrowser

Expand all

Signal Transduction (Rattus norvegicus)

- Signaling by GPCR (Rattus norvegicus)
  - GPCR downstream signalling (Rattus norvegicus)
    - G alpha (i) signalling events (Rattus norvegicus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        Group II and III metabotropic gutamate receptors:Glu [plasma membrane] (Rattus norvegicus)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Rattus norvegicus)
        
        GRM6 [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        Group II and III metabotropic gutamate receptors:Glu [plasma membrane] (Rattus norvegicus)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Rattus norvegicus)
        
        GRM6 [plasma membrane] (Rattus norvegicus)
  - GPCR ligand binding (Rattus norvegicus)
    - Class C/3 (Metabotropic glutamate/pheromone receptors) (Rattus norvegicus)
      - Metabotropic glutamate receptors bind glutamate (Rattus norvegicus)
        
        GRM1-8 [plasma membrane] (Rattus norvegicus)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Rattus norvegicus)
        
        GRM6 [plasma membrane] (Rattus norvegicus)
        
        GRM1-8:L-Glu [plasma membrane] (Rattus norvegicus)
        
        GRM1-8 [plasma membrane] (Rattus norvegicus)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Rattus norvegicus)
        
        GRM6 [plasma membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P35349

Reference Genes

BioGPS Gene:24419

ENSEMBL:ENSRNOG00000000233

ENSEMBL:ENSRNOG00000000233.7

KEGG Gene (Rattus norvegicus):24419

Monarch:24419

NCBI Gene:24419

UCSC:P35349

Reference Transcript

Other Identifiers

10733282

1387989_at

17645550

24419

5635136

5687656

5770587

5807429

5830559

5877353

5886780

5888031

6112904

6172831

6296097

6296678

6409414

6643850

A_44_P414242

A_64_P072558

D13963_at

GE21566

GO:0000139

GO:0004930

GO:0005783

GO:0005789

GO:0005794

GO:0005886

GO:0007165

GO:0007186

GO:0007216

GO:0007626

GO:0008066

GO:0016020

GO:0023052

GO:0035841

GO:0042803

GO:0043226

GO:0048856

GO:0050877

GO:0050908

GO:0050953

GO:0055085

GO:0060041

GO:0060089

GO:1905665

PH_rn_0020054

Participates

as a member of

GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Rattus norvegicus)

Inferred From

GRM6 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_075209.1, XP_017452483.1

ZINC - Metabolites

GRM6_RAT

ZINC - World Drugs

GRM6_RAT

ZINC - FDA approved

GRM6_RAT

ZINC - Substances

GRM6_RAT

ZINC - Biogenic

GRM6_RAT

ZINC target

P35349

Ensembl

ENSRNOP00000000249, ENSRNOT00000000249, ENSRNOG00000000233

PRO

P35349

RGD

2747

ZINC - Predictions - Purchasable

GRM6_RAT

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