Reactome | Pspn [extracellular region]

Pspn [extracellular region]

Stable Identifier

R-RNO-434907

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

extracellular region

Synonyms

PSPN, O70301

Locations in the PathwayBrowser

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Developmental Biology (Rattus norvegicus)

- Nervous system development (Rattus norvegicus)
  - Axon guidance (Rattus norvegicus)
    - RET signaling (Rattus norvegicus)
      - 2x p-5Y-RET:GDNF:GFRA complexes bind FRS2 (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:FRS2 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
      - 2x p-5Y-RET:GDNF:GFRA complexes bind GRB2-1:SOS1 (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1:SOS1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
      - 2x p-5Y-RET:GDNF:GFRA complexes bind GRB7,10 (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB7,GRB10 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
      - 2x p-5Y-RET:GDNF:GFRA complexes bind PLCgamma1 (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:PLCG1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
      - 2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:RET interactors [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
      - 2x p-5Y-RET:GDNF:GFRA complexes bind SHC1 (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:SHC1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
      - 2x p-5Y-RET:GDNF:GFRA complexes bind SRC1, RAP1GAP (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:SRC-1,RAP1GAP [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
      - 2x p-5Y-RET:GDNF:GFRA complexes binds DOK1,DOK2,DOK4,DOK5,DOK6 (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:DOK1,DOK2,DOK4,DOK5,DOK6 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
      - 2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 binds GRB2-1:SOS1 (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1:SOS1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
      - GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:GAB1,GAB2 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
      - PKA phosphorylates RET:GDNF:GFRA dimer (Rattus norvegicus)
        
        2x RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
      - PSPN binds RET:GFRA4 (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
      - RET dimerizes (Rattus norvegicus)
        
        2x RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
      - RET tyrosine phosphorylation (Rattus norvegicus)
        
        2x RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
      - SHC1 in the RET complex is phosphorylated (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:SHC1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
      - p-5Y-GAB in RET-GRB2-GAB complexes binds PTPN11 (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:PTPN11 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
      - p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
      - p-5Y-RET complexes bind GRB2 (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        p-5Y-RET:GDNF:GFRA complexes with and without p-SHC1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
      - p-5Y-RET-GRB2-containing complexes bind GAB1,GAB2 (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:GAB1,GAB2 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)

Signal Transduction (Rattus norvegicus)

- MAPK family signaling cascades (Rattus norvegicus)
  - MAPK1/MAPK3 signaling (Rattus norvegicus)
    - RAF/MAP kinase cascade (Rattus norvegicus)
      - RAS GEFs promote RAS nucleotide exchange (Rattus norvegicus)
        
        RAS GEFs [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1:SOS1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1:SOS1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Rattus norvegicus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Rattus norvegicus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Rattus norvegicus)
        
        Pspn [extracellular region] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:O70301

Gene Names

Pspn

Reference Genes

BioGPS Gene:25525 Pspn

ENSEMBL:ENSRNOG00000049171

ENSEMBL:ENSRNOG00000071190

ENSEMBL:ENSRNOG00000071190.1 Pspn

ENSEMBL:ENSRNOG00055014359

ENSEMBL:ENSRNOG00060022060

ENSEMBL:ENSRNOG00065013412

KEGG Gene (Rattus norvegicus):25525 Pspn

Monarch:25525 Pspn

NCBI Gene:25525 Pspn

Reference Transcript

RefSeq:NM_013014.1 Pspn

Other Identifiers

10930821

10930835

1383627_a_at

1385567_at

1387533_at

1393106_x_at

17867757

17867769

25525

5630211

5710126

5800926

5824702

5882294

5924622

5983476

6053954

6056300

6196012

6248401

6447338

6533320

6565475

6581871

6699636

6718855

6741972

AF040961_at

A_43_P11660

A_44_P527709

GE1165519

GE1199982

GO:0008083

GO:0030116

GO:0030971

GO:0048018

GO:0098772

ILMN_1359755

ILMN_1373227

PH_rn_0004138

PH_rn_0014450

rc_AA955573_at

rc_AA955573_g_at

rc_AI012037_at

Participates

as an input of

PSPN binds RET:GFRA4 (Rattus norvegicus)

as a component of

Inferred From

PSPN [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_037146.1

Ensembl

ENSRNOT00000114711, ENSRNOG00000071190, ENSRNOP00000077509

PRO

O70301

RGD

3432

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