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Nedd8 [cytosol]
Stable Identifier
R-RNO-4419895
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
C111-AcM-UBE2M-G76-NEDD8, Q71UE8
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Neddylation (Rattus norvegicus)
AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Rattus norvegicus)
NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
NEDD8-AcM-UBE2M [cytosol] (Rattus norvegicus)
Nedd8 [cytosol] (Rattus norvegicus)
AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex (Rattus norvegicus)
NEDD8-AcM-UBE2M:CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
NEDD8-AcM-UBE2M [cytosol] (Rattus norvegicus)
Nedd8 [cytosol] (Rattus norvegicus)
AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex (Rattus norvegicus)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
NEDD8-AcM-UBE2M [cytosol] (Rattus norvegicus)
Nedd8 [cytosol] (Rattus norvegicus)
AcM-UBE2M transfers NEDD8 to CUL9:RBX1 (Rattus norvegicus)
NEDD8-AcM-UBE2M:CUL9:RBX1 [cytosol] (Rattus norvegicus)
NEDD8-AcM-UBE2M [cytosol] (Rattus norvegicus)
Nedd8 [cytosol] (Rattus norvegicus)
NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Rattus norvegicus)
NEDD8-AcM-UBE2M [cytosol] (Rattus norvegicus)
Nedd8 [cytosol] (Rattus norvegicus)
NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
NEDD8-AcM-UBE2M [cytosol] (Rattus norvegicus)
Nedd8 [cytosol] (Rattus norvegicus)
NEDD8:AcM-UBE2M binds CRL2 E3 ubiquitin ligase complex (Rattus norvegicus)
NEDD8-AcM-UBE2M [cytosol] (Rattus norvegicus)
Nedd8 [cytosol] (Rattus norvegicus)
NEDD8-AcM-UBE2M:CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
NEDD8-AcM-UBE2M [cytosol] (Rattus norvegicus)
Nedd8 [cytosol] (Rattus norvegicus)
NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex (Rattus norvegicus)
NEDD8-AcM-UBE2M [cytosol] (Rattus norvegicus)
Nedd8 [cytosol] (Rattus norvegicus)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
NEDD8-AcM-UBE2M [cytosol] (Rattus norvegicus)
Nedd8 [cytosol] (Rattus norvegicus)
NEDD8:AcM-UBE2M binds CUL9:RBX1 ubiquitin ligase complex (Rattus norvegicus)
NEDD8-AcM-UBE2M [cytosol] (Rattus norvegicus)
Nedd8 [cytosol] (Rattus norvegicus)
NEDD8-AcM-UBE2M:CUL9:RBX1 [cytosol] (Rattus norvegicus)
NEDD8-AcM-UBE2M [cytosol] (Rattus norvegicus)
Nedd8 [cytosol] (Rattus norvegicus)
Transfer of NEDD8 to AcM-UBE2M (Rattus norvegicus)
NEDD8-AcM-UBE2M [cytosol] (Rattus norvegicus)
Nedd8 [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Signaling by TGFB family members (Rattus norvegicus)
Signaling by TGF-beta Receptor Complex (Rattus norvegicus)
TGF-beta receptor signaling activates SMADs (Rattus norvegicus)
CBL neddylates TGFBR2 (Rattus norvegicus)
NEDD8-AcM-UBE2M [cytosol] (Rattus norvegicus)
Nedd8 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:Q71UE8
Gene Names
Nedd8
Reference Genes
BioGPS Gene:25490 Nedd8
ENSEMBL:ENSRNOG00000019895
ENSEMBL:ENSRNOG00000019895.7 Nedd8
ENSEMBL:ENSRNOG00055012620
ENSEMBL:ENSRNOG00060023791
ENSEMBL:ENSRNOG00065033388
KEGG Gene (Rattus norvegicus):25490 Nedd8
Monarch:25490 Nedd8
NCBI Gene:25490 Nedd8
UCSC:Q71UE8 Nedd8
Reference Transcript
RefSeq:NM_138878.2 Nedd8
Other Identifiers
10783863
1398860_at
17702990
25490
6038135
6114574
6379364
6393357
6487552
6746824
AA685152_r_at
A_64_P152731
GE21407
GO:0005515
ILMN_1353274
PH_rn_0013769
rc_AA892544_s_at
Participates
as a component of
NEDD8-AcM-UBE2M [cytosol] (Rattus norvegicus)
Other forms of this molecule
Nedd8 [nucleoplasm]
Nedd8 [nucleoplasm]
Nedd8 [cytosol]
Nedd8 [cytosol]
Nedd8 [cytosol]
Nedd8 [cytosol]
Nedd8 [cytosol]
Inferred From
C111-AcM-UBE2M-G76-NEDD8 [cytosol]
(Homo sapiens)
Modified Residues
Name
Inter-chain Crosslink via S-(glycyl)-L-cysteine (Cys-Gly) at 76 and 111 (in Homo sapiens)
Coordinate
76
PsiMod Name
S-(glycyl)-L-cysteine (Cys-Gly)
PsiMod Definition
A protein modification that effectively crosslinks an L-cysteine residue and a glycine residue by a thioester bond to form S-glycyl-L-cysteine.
Cross References
RefSeq
NP_620233.1
Ensembl
ENSRNOP00000061284
,
ENSRNOT00000064916
,
ENSRNOG00000019895
PRO
Q71UE8
RGD
3158
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