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About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
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TAK1 complex [cytosol]
Stable Identifier
R-RNO-446878
Type
Complex
Species
Rattus norvegicus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Rattus norvegicus)
Cytokine Signaling in Immune system (Rattus norvegicus)
Signaling by Interleukins (Rattus norvegicus)
Interleukin-1 family signaling (Rattus norvegicus)
Interleukin-1 signaling (Rattus norvegicus)
Polyubiquitinated TRAF6 binds the TAK1 complex (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:K6-poly-Ub oligo-TRAF6:TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 is activated within the TAK1 complex (Rattus norvegicus)
hp-IRAK1:K6-poly-Ub oligo-TRAF6:TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 phosphorylates MKK6 (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
Interleukin-17 signaling (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
Innate Immune System (Rattus norvegicus)
Alpha-protein kinase 1 signaling pathway (Rattus norvegicus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
C-type lectin receptors (CLRs) (Rattus norvegicus)
CLEC7A (Dectin-1) signaling (Rattus norvegicus)
TRIKA2 binds K63polyUb-TRAF6 oligomer (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TRIKA2 [plasma membrane] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
Fc epsilon receptor (FCERI) signaling (Rattus norvegicus)
FCERI mediated NF-kB activation (Rattus norvegicus)
Activation of TAK1 complex bound to pUb-TRAF6 (Rattus norvegicus)
DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
Phosphorylation of IKK-beta by TAK1 (Rattus norvegicus)
DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 (Rattus norvegicus)
DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Rattus norvegicus)
NOD1/2 Signaling Pathway (Rattus norvegicus)
TAK1 is activated (Rattus norvegicus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 phosphorylates MKK6 (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
Toll-like Receptor Cascades (Rattus norvegicus)
Toll Like Receptor 10 (TLR10) Cascade (Rattus norvegicus)
MyD88 cascade initiated on plasma membrane (Rattus norvegicus)
IRAK2 mediated activation of TAK1 complex (Rattus norvegicus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Rattus norvegicus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
Toll Like Receptor 2 (TLR2) Cascade (Rattus norvegicus)
Toll Like Receptor TLR1:TLR2 Cascade (Rattus norvegicus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
IRAK2 mediated activation of TAK1 complex (Rattus norvegicus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Rattus norvegicus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
Toll Like Receptor TLR6:TLR2 Cascade (Rattus norvegicus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
IRAK2 mediated activation of TAK1 complex (Rattus norvegicus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Rattus norvegicus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
Toll Like Receptor 3 (TLR3) Cascade (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
Toll Like Receptor 4 (TLR4) Cascade (Rattus norvegicus)
MyD88-independent TLR4 cascade (Rattus norvegicus)
TRIF (TICAM1)-mediated TLR4 signaling (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
TRAF6-mediated induction of TAK1 complex within TLR4 complex (Rattus norvegicus)
Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
Activation of TAK1 complex bound to activated TLR4 complex (Rattus norvegicus)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
IRAK2 mediated activation of TAK1 complex (Rattus norvegicus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Rattus norvegicus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
Toll Like Receptor 5 (TLR5) Cascade (Rattus norvegicus)
MyD88 cascade initiated on plasma membrane (Rattus norvegicus)
IRAK2 mediated activation of TAK1 complex (Rattus norvegicus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Rattus norvegicus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Rattus norvegicus)
MyD88 dependent cascade initiated on endosome (Rattus norvegicus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Rattus norvegicus)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Rattus norvegicus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
Toll Like Receptor 9 (TLR9) Cascade (Rattus norvegicus)
MyD88 dependent cascade initiated on endosome (Rattus norvegicus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Rattus norvegicus)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Rattus norvegicus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Death Receptor Signaling (Rattus norvegicus)
TNF signaling (Rattus norvegicus)
TNFR1-induced NF-kappa-B signaling pathway (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIP1:LUBAC:BIRC2/3:TAB1:TAK1:TAB2/3 [plasma membrane] (Rattus norvegicus)
TAK1 complex [cytosol] (Rattus norvegicus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
MAP3K7 [cytosol]
(Rattus norvegicus)
Tab1 [cytosol]
(Rattus norvegicus)
TAB2,TAB3 [cytosol]
(Rattus norvegicus)
Participates
as an input of
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex (Rattus norvegicus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation (Rattus norvegicus)
Polyubiquitinated TRAF6 binds the TAK1 complex (Rattus norvegicus)
TRIKA2 binds K63polyUb-TRAF6 oligomer (Rattus norvegicus)
Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 (Rattus norvegicus)
Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex (Rattus norvegicus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) (Rattus norvegicus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Rattus norvegicus)
as a component of
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIP1:LUBAC:BIRC2/3:TAB1:TAK1:TAB2/3 [plasma membrane] (Rattus norvegicus)
hp-IRAK1:K6-poly-Ub oligo-TRAF6:TAK1 complex [cytosol] (Rattus norvegicus)
p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TRIKA2 [plasma membrane] (Rattus norvegicus)
DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] (Rattus norvegicus)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] (Rattus norvegicus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Rattus norvegicus)
Inferred From
TAB1:TAB2,TAB3:TAK1 [cytosol]
(Homo sapiens)
TAK1 complex [cytosol]
(Homo sapiens)
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