Reactome | Il2ra [plasma membrane]

Il2ra [plasma membrane]

Stable Identifier

R-RNO-450046

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

IL2RA, P26897

Locations in the PathwayBrowser

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Immune System (Rattus norvegicus)

- Cytokine Signaling in Immune system (Rattus norvegicus)
  - Signaling by Interleukins (Rattus norvegicus)
    - Interleukin-2 family signaling (Rattus norvegicus)
      - Interleukin receptor SHC signaling (Rattus norvegicus)
        
        Gab2 binds the p85 subunit of Class 1A PI3 kinases (Rattus norvegicus)
        
        Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p(Y338) beta subunit:p-SHC:GRB2:GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        Phosphorylated SHC recruits GRB2:SOS1 (Rattus norvegicus)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        Phosphorylated SHC1 recruits GRB2:GAB2 (Rattus norvegicus)
        
        Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:GAB2 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        Phosphorylated SHC1 recruits SHIP (Rattus norvegicus)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Rattus norvegicus)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        SHC1 mediates cytokine-induced phosphorylation of GAB2 (Rattus norvegicus)
        
        Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:GAB2 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        The SHC1:SHIP1 complex is stabilized by GRB2 (Rattus norvegicus)
        
        Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Rattus norvegicus)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Rattus norvegicus)
        
        Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Rattus norvegicus)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
      - Interleukin-2 signaling (Rattus norvegicus)
        
        Interleukin-2 receptor alpha binds interleukin-2 (Rattus norvegicus)
        
        IL2:IL2RA [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        Interleukin-2 receptor alpha:IL2 binds Interleukin-2 receptor beta (Rattus norvegicus)
        
        IL2:IL2RA [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2RA:IL2RB:JAK1 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2RA [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        IL2RA:IL2RB:p-JAK1:IL2 [plasma membrane] (Rattus norvegicus)
        
        IL2RA:IL2RB:p-JAK1 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        Phosphorylated STAT5 is released (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,Y392, Y510) beta subunit:p-JAK1:JAK3:p-STAT5 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        Phosphorylation of IL2RB Y338 enables SHC recruitment (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        Phosphorylation of IL2RB Y338, Y392 or Y510 enables STAT recruitment (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3:STAT5 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        Recruited STAT5 is phosphorylated (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3:STAT5 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,Y392, Y510) beta subunit:p-JAK1:JAK3:p-STAT5 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        SHC1 bound to IL2 receptor is phosphorylated (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        SYK binds IL2RB (Rattus norvegicus)
        
        IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        IL2RA:IL2RB:p-JAK1:IL2 [plasma membrane] (Rattus norvegicus)
        
        IL2RA:IL2RB:p-JAK1 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer:p-JAK1:JAK3:SYK [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        IL2RA:IL2RB:p-JAK1:IL2 [plasma membrane] (Rattus norvegicus)
        
        IL2RA:IL2RB:p-JAK1 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        SYK is a substrate for JAK1 (Rattus norvegicus)
        
        IL2:IL2R trimer:p-JAK1:JAK3:SYK [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        IL2RA:IL2RB:p-JAK1:IL2 [plasma membrane] (Rattus norvegicus)
        
        IL2RA:IL2RB:p-JAK1 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer:p-JAK1:JAK3:p-SYK [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        IL2RA:IL2RB:p-JAK1:IL2 [plasma membrane] (Rattus norvegicus)
        
        IL2RA:IL2RB:p-JAK1 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        Within the IL-2R complex JAK3 phosphorylates JAK1 (Rattus norvegicus)
        
        IL2:IL2R trimer:JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2RA:IL2RB:JAK1 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2RA [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        IL2RA:IL2RB:p-JAK1:IL2 [plasma membrane] (Rattus norvegicus)
        
        IL2RA:IL2RB:p-JAK1 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
    - Interleukin-3, Interleukin-5 and GM-CSF signaling (Rattus norvegicus)
      - Interleukin receptor SHC signaling (Rattus norvegicus)
        
        Gab2 binds the p85 subunit of Class 1A PI3 kinases (Rattus norvegicus)
        
        Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p(Y338) beta subunit:p-SHC:GRB2:GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        Phosphorylated SHC recruits GRB2:SOS1 (Rattus norvegicus)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        Phosphorylated SHC1 recruits GRB2:GAB2 (Rattus norvegicus)
        
        Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:GAB2 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        Phosphorylated SHC1 recruits SHIP (Rattus norvegicus)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Rattus norvegicus)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        SHC1 mediates cytokine-induced phosphorylation of GAB2 (Rattus norvegicus)
        
        Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:GAB2 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        The SHC1:SHIP1 complex is stabilized by GRB2 (Rattus norvegicus)
        
        Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Rattus norvegicus)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)
        
        Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Rattus norvegicus)
        
        Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Rattus norvegicus)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)

Signal Transduction (Rattus norvegicus)

- MAPK family signaling cascades (Rattus norvegicus)
  - MAPK1/MAPK3 signaling (Rattus norvegicus)
    - RAF/MAP kinase cascade (Rattus norvegicus)
      - RAS GEFs promote RAS nucleotide exchange (Rattus norvegicus)
        
        RAS GEFs [plasma membrane] (Rattus norvegicus)
        
        Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Rattus norvegicus)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Rattus norvegicus)
        
        Il2ra [plasma membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P26897

Gene Names

Il2ra

Reference Genes

BioGPS Gene:25704 Il2ra

ENSEMBL:ENSRNOG00000047647

ENSEMBL:ENSRNOG00000047647.3 Il2ra

KEGG Gene (Rattus norvegicus):25704 Il2ra

Monarch:25704 Il2ra

NCBI Gene:25704 Il2ra

UCSC:P26897 Il2ra

Reference Transcript

RefSeq:NM_013163.1 Il2ra

Other Identifiers

10799420

1387591_at

17720596

25704

5826665

5832908

5885052

5893575

5906037

6047949

6073674

6168108

6428891

6481314

6681531

6730179

A_43_P11741

A_44_P452261

GE21809

GO:0002376

GO:0002664

GO:0004911

GO:0005886

GO:0006924

GO:0006954

GO:0007155

GO:0007219

GO:0009897

GO:0012501

GO:0019976

GO:0023052

GO:0038110

GO:0042104

GO:0042130

GO:0043029

GO:0046013

GO:0046651

GO:0048856

GO:0050672

GO:0050728

GO:0050798

GO:0060089

GO:2000561

ILMN_1370832

M55049_at

rc_AI059735_at

Participates

as an input of

Interleukin-2 receptor alpha binds interleukin-2 (Rattus norvegicus)

as a component of

Inferred From

IL2RA [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_037295.1

Ensembl

ENSRNOG00000047647, ENSRNOT00000073144, ENSRNOP00000066383

PRO

P26897

RGD

2895

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