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MAP3K7 [endosome membrane]
Stable Identifier
R-RNO-450315
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
endosome membrane
Synonyms
P0C8E4
Locations in the PathwayBrowser
Expand all
Immune System (Rattus norvegicus)
Innate Immune System (Rattus norvegicus)
Toll-like Receptor Cascades (Rattus norvegicus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Rattus norvegicus)
MyD88 dependent cascade initiated on endosome (Rattus norvegicus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Rattus norvegicus)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Rattus norvegicus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation (Rattus norvegicus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [endosome membrane] (Rattus norvegicus)
TAK1 complex [endosome membrane] (Rattus norvegicus)
MAP3K7 [endosome membrane] (Rattus norvegicus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Rattus norvegicus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [endosome membrane] (Rattus norvegicus)
TAK1 complex [endosome membrane] (Rattus norvegicus)
MAP3K7 [endosome membrane] (Rattus norvegicus)
Toll Like Receptor 9 (TLR9) Cascade (Rattus norvegicus)
MyD88 dependent cascade initiated on endosome (Rattus norvegicus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Rattus norvegicus)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Rattus norvegicus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation (Rattus norvegicus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [endosome membrane] (Rattus norvegicus)
TAK1 complex [endosome membrane] (Rattus norvegicus)
MAP3K7 [endosome membrane] (Rattus norvegicus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Rattus norvegicus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [endosome membrane] (Rattus norvegicus)
TAK1 complex [endosome membrane] (Rattus norvegicus)
MAP3K7 [endosome membrane] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P0C8E4
Reference Genes
BioGPS Gene:313121
ENSEMBL:ENSRNOG00000005724
ENSEMBL:ENSRNOG00000005724.6
ENSEMBL:ENSRNOG00000047516
ENSEMBL:ENSRNOG00055010068
ENSEMBL:ENSRNOG00060013880
ENSEMBL:ENSRNOG00065005799
KEGG Gene (Rattus norvegicus):313121
Monarch:313121
NCBI Gene:313121
UCSC:P0C8E4
Reference Transcript
RefSeq:NM_001107920.2
RefSeq:XM_003750753.4
Other Identifiers
10867979
1399075_at
17797678
313121
5632015
5710253
5780967
5793660
5841334
5843139
6012233
6099588
6193638
6205467
6212437
6229299
6307916
6321232
6344630
6374712
6379254
6429451
6512814
6582780
6602374
6616764
6691410
6693495
A_44_P300018
A_44_P932802
A_64_P021723
GE1194592
GE1213365
GO:0000165
GO:0000287
GO:0002376
GO:0002726
GO:0003824
GO:0004672
GO:0004674
GO:0004707
GO:0004709
GO:0005524
GO:0005694
GO:0005737
GO:0005829
GO:0005886
GO:0006468
GO:0006954
GO:0007165
GO:0007249
GO:0007254
GO:0016740
GO:0023052
GO:0030971
GO:0032743
GO:0034142
GO:0036211
GO:0038066
GO:0038172
GO:0038173
GO:0042742
GO:0042802
GO:0043123
GO:0043226
GO:0051403
GO:0070498
GO:0097110
GO:0098542
GO:0140096
GO:0140672
GO:1901224
GO:1990450
ILMN_1371190
PH_rn_0014665
PH_rn_0020639
rc_AI146037_at
Participates
as a component of
TAK1 complex [endosome membrane] (Rattus norvegicus)
Other forms of this molecule
PolyUb-MAP3K7 [cytosol]
phospho-p-T187-MAP3K7 [cytosol]
K63polyUb-34,158-TAK1 [cytosol]
phospho-K63polyUb-34,158-p-T178,184,187,S192-TAK1 [cytosol]
phospho-p-MAP3K7 [cytosol]
phospho-p-T184,T187-MAP3K7 [endosome membrane]
MAP3K7 [cytosol]
phospho-p-T184,T187-MAP3K7 [cytosol]
Inferred From
MAP3K7 [endosome membrane]
(Homo sapiens)
Cross References
RefSeq
NP_001101390.2
,
XP_003750801.1
Ensembl
ENSRNOP00000007654
,
ENSRNOG00000005724
,
ENSRNOT00000007654
PRO
P0C8E4
RGD
1309438
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