Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Vhl [nucleoplasm]
Stable Identifier
R-RNO-4551697
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
nucleoplasm
Synonyms
monoSUMO1-K159,171,196-VHL, Q64259
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
SUMOylation (Rattus norvegicus)
SUMO E3 ligases SUMOylate target proteins (Rattus norvegicus)
SUMOylation of ubiquitinylation proteins (Rattus norvegicus)
PIAS4 SUMOylates VHL with SUMO1 (Rattus norvegicus)
Vhl [nucleoplasm] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:Q64259
Gene Names
Vhl
Reference Genes
BioGPS Gene:24874 Vhl
ENSEMBL:ENSRNOG00000010258
ENSEMBL:ENSRNOG00055009089
ENSEMBL:ENSRNOG00060013774
ENSEMBL:ENSRNOG00065028191
KEGG:rno:24874 Vhl
Monarch:24874 Vhl
NCBI Gene:24874 Vhl
UCSC:Q64259 Vhl
Reference Transcript
RefSeq:NM_052801.1 Vhl
Other Identifiers
10857887
1368076_at
17786163
24874
5925141
5947369
5967964
6223944
6228116
6228879
6337804
6512455
A_44_P1017315
A_44_P477135
A_64_P005749
GE20865
GO:0001525
GO:0003309
GO:0003310
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0005929
GO:0006582
GO:0010468
GO:0010498
GO:0010629
GO:0012501
GO:0014069
GO:0015031
GO:0023052
GO:0030154
GO:0030163
GO:0030198
GO:0031462
GO:0032880
GO:0034330
GO:0043226
GO:0043534
GO:0044877
GO:0045446
GO:0045602
GO:0048069
GO:0048593
GO:0048856
GO:0048870
GO:0048877
GO:0050679
GO:0061072
GO:0061073
GO:0070243
GO:0070244
GO:0097411
GO:0098978
GO:0099175
GO:0140252
GO:1902072
GO:2001233
ILMN_1367225
PH_rn_0006403
S80345_s_at
U14746_at
Participates
as an output of
PIAS4 SUMOylates VHL with SUMO1 (Rattus norvegicus)
Other forms of this molecule
Vhl [nucleoplasm]
Vhl [cytosol]
Inferred From
monoSUMO1-K159,171,196-VHL [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
sumoylated lysine (monoSUMO1 [nucleoplasm]) at 159 (in Homo sapiens)
Coordinate
159
Modification
monoSUMO1 [nucleoplasm]
PsiMod Name
sumoylated lysine
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Name
sumoylated lysine (monoSUMO1 [nucleoplasm]) at 171 (in Homo sapiens)
Coordinate
171
Modification
monoSUMO1 [nucleoplasm]
PsiMod Name
sumoylated lysine
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Name
sumoylated lysine (monoSUMO1 [nucleoplasm]) at 196 (in Homo sapiens)
Coordinate
196
Modification
monoSUMO1 [nucleoplasm]
PsiMod Name
sumoylated lysine
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Cross References
RefSeq
NP_434688.1
ENSEMBL
ENSRNOP00000013727
,
ENSRNOT00000013727
PRO
Q64259
RGD
3960
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text