Reactome | Axin1 [cytosol]

Axin1 [cytosol]

Stable Identifier

R-RNO-4641133

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

ub-AXIN1, O70239

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O70239

Gene Names

Axin1

Reference Genes

BioGPS Gene:79257 Axin1

ENSEMBL:ENSRNOG00000062714

KEGG:rno:79257 Axin1

Monarch:79257 Axin1

NCBI Gene:79257 Axin1

UCSC:O70239 Axin1

Reference Transcript

RefSeq:NM_024405.1 Axin1

Participates

as a member of

ub-AXIN [cytosol] (Rattus norvegicus)

Other forms of this molecule

phospho-Axin1 [cytosol]

Axin1 [cytosol]

Inferred From

ub-AXIN1 [cytosol] (Homo sapiens)

Modified Residues

Name

ubiquitinylated lysine (K48polyUb [cytosol]) at 505 (in Homo sapiens)

Coordinate

505

Modification

K48polyUb [cytosol]

PsiMod Name

ubiquitinylated lysine [MOD:01148]

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.

Cross References

RefSeq

NP_077381.1

PRO

O70239

RGD

620859

PDB

2D5G, 1WSP

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O14640 DVL1	4	ub-DVL1 [cytosol] (R-HSA-4641157) DVL1 [cytosol] (R-HSA-201687) p-S-DVL1 [cytosol] (R-HSA-201700) pp-DVL1 [cytosol] (R-HSA-3772396)	0.796	12
UniProt:O70239	5	phospho-Axin1 [cytosol] (R-RNO-3640864) phospho-Axin1 [cytosol] (R-RNO-3640841) Axin1 [cytosol] (R-RNO-4641133) phospho-Axin1 [cytosol] (R-RNO-206040) Axin1 [cytosol] (R-RNO-195249)	0.729	5
UniProt:O75581 LRP6	8	LRP6 [plasma membrane] (R-HSA-206252) p-4S,3T,T1479,S1490,T1493-LRP6 [plasma membrane] (R-HSA-1458895) p-2S,S1490,2T-LRP6 [plasma membrane] (R-HSA-1458894) LRP6N [extracellular region] (R-HSA-5334021) p-LRP6 [early endosome membrane] (R-HSA-5368496) LRP6 [early endosome membrane] (R-HSA-5368481) p-S1490-LRP6 [plasma membrane] (R-HSA-206156) p-T1479,S1490,T1493-LRP6 [plasma membrane] (R-HSA-205884)	0.602	12
UniProt:P49674 CSNK1E	2	CSNK1E [cytosol] (R-HSA-205877) CSNK1E [nucleoplasm] (R-HSA-421306)	0.591	7
UniProt:Q9Y4X0 AMMR1			0.499	3
IntAct:EBI-6876714 GSK3B			0.499	4
UniProt:Q03135 CAV1	5	CAV1 [Golgi membrane] (R-HSA-204504) CAV1 [plasma membrane] (R-HSA-534994) CAV1 [lipid droplet] (R-HSA-163510) CAV1 [endocytic vesicle membrane] (R-HSA-535009) CAV1 [early endosome membrane] (R-HSA-5368451)	0.463	5

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