Reactome | Ccnt1 [nucleoplasm]

Ccnt1 [nucleoplasm]

Stable Identifier

R-RNO-51611

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

CCNT1, D3ZC98

Locations in the PathwayBrowser

Expand all

Signal Transduction (Rattus norvegicus)

- Signaling by Nuclear Receptors (Rattus norvegicus)
  - ESR-mediated signaling (Rattus norvegicus)
    - Estrogen-dependent gene expression (Rattus norvegicus)
      - ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene (Rattus norvegicus)
        
        ESR1:ESTG:P-TEFb [nucleoplasm] (Rattus norvegicus)
        
        P-TEFb(Cyclin T1:Cdk9) complex [nucleoplasm] (Rattus norvegicus)
        
        Ccnt1 [nucleoplasm] (Rattus norvegicus)
        
        MYB gene:hypophosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFb [nucleoplasm] (Rattus norvegicus)
        
        ESR1:ESTG:P-TEFb [nucleoplasm] (Rattus norvegicus)
        
        P-TEFb(Cyclin T1:Cdk9) complex [nucleoplasm] (Rattus norvegicus)
        
        Ccnt1 [nucleoplasm] (Rattus norvegicus)
      - p-TEFb phosphorylates serine 2 in RNA polymerase II CTD (Rattus norvegicus)
        
        MYB gene:hyperphosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFb [nucleoplasm] (Rattus norvegicus)
        
        ESR1:ESTG:P-TEFb [nucleoplasm] (Rattus norvegicus)
        
        P-TEFb(Cyclin T1:Cdk9) complex [nucleoplasm] (Rattus norvegicus)
        
        Ccnt1 [nucleoplasm] (Rattus norvegicus)
        
        MYB gene:hypophosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFb [nucleoplasm] (Rattus norvegicus)
        
        ESR1:ESTG:P-TEFb [nucleoplasm] (Rattus norvegicus)
        
        P-TEFb(Cyclin T1:Cdk9) complex [nucleoplasm] (Rattus norvegicus)
        
        Ccnt1 [nucleoplasm] (Rattus norvegicus)
- Signaling by TGFB family members (Rattus norvegicus)
  - Signaling by TGF-beta Receptor Complex (Rattus norvegicus)
    - Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Rattus norvegicus)
      - SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Rattus norvegicus)
        
        Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 (Rattus norvegicus)
        
        P-TEFb complex [nucleoplasm] (Rattus norvegicus)
        
        CCNT1,CCNT2,CCNK [nucleoplasm] (Rattus norvegicus)
        
        Ccnt1 [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:D3ZC98

Gene Names

Ccnt1

Reference Genes

BioGPS Gene:315291 Ccnt1

ENSEMBL:ENSRNOG00000053054

ENSEMBL:ENSRNOG00000053054 Ccnt1

KEGG Gene (Rattus norvegicus):315291 Ccnt1

Monarch:315291 Ccnt1

NCBI Gene:315291 Ccnt1

Reference Transcript

RefSeq:NM_001108110.1 Ccnt1

Other Identifiers

10906872

17840726

315291

5707753

5862998

5916946

5979998

5995575

6089647

6093660

6314248

6428729

6434875

6435482

6563685

6734885

A_44_P504221

GO:0000079

GO:0000976

GO:0003674

GO:0003677

GO:0003682

GO:0003723

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0006351

GO:0006357

GO:0006397

GO:0006464

GO:0006468

GO:0007049

GO:0008024

GO:0008134

GO:0008150

GO:0009058

GO:0016538

GO:0017069

GO:0019899

GO:0019901

GO:0030234

GO:0032786

GO:0032991

GO:0034641

GO:0042025

GO:0042493

GO:0043226

GO:0045737

GO:0045944

GO:0061575

GO:0070063

GO:0097322

GO:1900364

ILMN_1369043

PH_rn_0010504

Participant Of

hasComponent

P-TEFb(Cyclin T1:Cdk9) complex [nucleoplasm]

hasMember

CCNT1,CCNT2,CCNK [nucleoplasm]

Inferred From

CCNT1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001101580.1

Ensembl

ENSRNOT00000088999, ENSRNOP00000073281, ENSRNOG00000053054

RGD

1311151

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