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CYCS [cytosol]
Stable Identifier
R-RNO-53259-3
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
P62898
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Rattus norvegicus)
Apoptosis (Rattus norvegicus)
Intrinsic Pathway for Apoptosis (Rattus norvegicus)
Apoptotic factor-mediated response (Rattus norvegicus)
Cytochrome c-mediated apoptotic response (Rattus norvegicus)
Activation of caspases through apoptosome-mediated cleavage (Rattus norvegicus)
Cleavage of Procaspase-3 by the apoptosome (Rattus norvegicus)
Apoptosome [cytosol] (Rattus norvegicus)
APAF1:CYCS [cytosol] (Rattus norvegicus)
Homologues of CYCS [cytosol] (Rattus norvegicus)
CYCS [cytosol] (Rattus norvegicus)
Cleavage of Procaspase-7 by the apoptosome (Rattus norvegicus)
Apoptosome [cytosol] (Rattus norvegicus)
APAF1:CYCS [cytosol] (Rattus norvegicus)
Homologues of CYCS [cytosol] (Rattus norvegicus)
CYCS [cytosol] (Rattus norvegicus)
Formation of apoptosome (Rattus norvegicus)
CYCS binds to APAF1 (Rattus norvegicus)
APAF1:ATP:CYCS [cytosol] (Rattus norvegicus)
Homologues of CYCS [cytosol] (Rattus norvegicus)
CYCS [cytosol] (Rattus norvegicus)
Homologues of CYCS [cytosol] (Rattus norvegicus)
CYCS [cytosol] (Rattus norvegicus)
CYCS:APAF1 binds procaspase-9 (Rattus norvegicus)
APAF1:ATP:CYCS [cytosol] (Rattus norvegicus)
Homologues of CYCS [cytosol] (Rattus norvegicus)
CYCS [cytosol] (Rattus norvegicus)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Rattus norvegicus)
APAF1:ATP:CYCS [cytosol] (Rattus norvegicus)
Homologues of CYCS [cytosol] (Rattus norvegicus)
CYCS [cytosol] (Rattus norvegicus)
Cleavage of Procaspase‑9 to caspase‑9 (Rattus norvegicus)
APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol] (Rattus norvegicus)
APAF1:CYCS [cytosol] (Rattus norvegicus)
Homologues of CYCS [cytosol] (Rattus norvegicus)
CYCS [cytosol] (Rattus norvegicus)
Apoptosome [cytosol] (Rattus norvegicus)
APAF1:CYCS [cytosol] (Rattus norvegicus)
Homologues of CYCS [cytosol] (Rattus norvegicus)
CYCS [cytosol] (Rattus norvegicus)
Procaspase 9 forms dimer (Rattus norvegicus)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Rattus norvegicus)
APAF1:ATP:CYCS [cytosol] (Rattus norvegicus)
Homologues of CYCS [cytosol] (Rattus norvegicus)
CYCS [cytosol] (Rattus norvegicus)
APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol] (Rattus norvegicus)
APAF1:CYCS [cytosol] (Rattus norvegicus)
Homologues of CYCS [cytosol] (Rattus norvegicus)
CYCS [cytosol] (Rattus norvegicus)
Regulation of the apoptosome activity (Rattus norvegicus)
APAF1:CYCS binds APIP (Rattus norvegicus)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Rattus norvegicus)
APAF1:ATP:CYCS [cytosol] (Rattus norvegicus)
Homologues of CYCS [cytosol] (Rattus norvegicus)
CYCS [cytosol] (Rattus norvegicus)
APAF1:CYCS:ATP:APIP [cytosol] (Rattus norvegicus)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Rattus norvegicus)
APAF1:ATP:CYCS [cytosol] (Rattus norvegicus)
Homologues of CYCS [cytosol] (Rattus norvegicus)
CYCS [cytosol] (Rattus norvegicus)
CASP9 is phosphorylated at T412 (Rattus norvegicus)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Rattus norvegicus)
APAF1:ATP:CYCS [cytosol] (Rattus norvegicus)
Homologues of CYCS [cytosol] (Rattus norvegicus)
CYCS [cytosol] (Rattus norvegicus)
APAF1:ATP:CYCS heptamer:p-T412-CASP9 [cytosol] (Rattus norvegicus)
APAF1:ATP:CYCS [cytosol] (Rattus norvegicus)
Homologues of CYCS [cytosol] (Rattus norvegicus)
CYCS [cytosol] (Rattus norvegicus)
XIAP binds CASP9 (Rattus norvegicus)
Apoptosome [cytosol] (Rattus norvegicus)
APAF1:CYCS [cytosol] (Rattus norvegicus)
Homologues of CYCS [cytosol] (Rattus norvegicus)
CYCS [cytosol] (Rattus norvegicus)
XIAP:apoptosome [cytosol] (Rattus norvegicus)
Apoptosome [cytosol] (Rattus norvegicus)
APAF1:CYCS [cytosol] (Rattus norvegicus)
Homologues of CYCS [cytosol] (Rattus norvegicus)
CYCS [cytosol] (Rattus norvegicus)
Release of apoptotic factors from the mitochondria (Rattus norvegicus)
Release of Cytochrome c from mitochondria (Rattus norvegicus)
Homologues of CYCS [cytosol] (Rattus norvegicus)
CYCS [cytosol] (Rattus norvegicus)
Regulated Necrosis (Rattus norvegicus)
Pyroptosis (Rattus norvegicus)
Release of Cytochrome c from mitochondria (Rattus norvegicus)
Homologues of CYCS [cytosol] (Rattus norvegicus)
CYCS [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P62898
Reference Genes
BioGPS Gene:25309
ENSEMBL:ENSRNOG00000010452
ENSEMBL:ENSRNOG00000010452.8
ENSEMBL:ENSRNOG00000065095
ENSEMBL:ENSRNOG00000065095.1
ENSEMBL:ENSRNOG00055010600
ENSEMBL:ENSRNOG00055026915
ENSEMBL:ENSRNOG00060010835
ENSEMBL:ENSRNOG00060026085
ENSEMBL:ENSRNOG00065014463
ENSEMBL:ENSRNOG00065023326
KEGG Gene (Rattus norvegicus):100363502
KEGG Gene (Rattus norvegicus):25309
Monarch:25309
NCBI Gene:25309
UCSC:P62898
Reference Transcript
RefSeq:XM_003753058.4
RefSeq:XM_003751799.4
RefSeq:NM_012839.2
Other Identifiers
10742474
10804954
10862501
1369939_at
1387773_at
1397987_at
17655936
17726838
17791312
25309
5839816
6015754
6401704
6521321
6581619
6619697
6622168
6703759
A_43_P14175
A_44_P554332
A_44_P851810
A_64_P085837
A_64_P085841
GE20000
GO:0003824
GO:0006091
GO:0009055
GO:0016491
GO:0020037
ILMN_1371982
K00750exon#2-3_at
K00750exon#2-3_g_at
PH_rn_0013610
rc_AI008815_s_at
Participates
as a member of
Homologues of CYCS [cytosol] (Rattus norvegicus)
Other forms of this molecule
AcK-CYCS [mitochondrial intermembrane space]
CYCS [mitochondrial inner membrane]
CYCS [mitochondrial intermembrane space]
Inferred From
CYCS [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_003751847.1
,
NP_036971.1
,
XP_003753106.1
Ensembl
ENSRNOT00000014058
,
ENSRNOT00000102631
,
ENSRNOP00000094836
,
ENSRNOP00000014058
,
ENSRNOG00000010452
,
ENSRNOG00000065095
PRO
P62898
RGD
2451
PDB
6N1O
,
5DF5
,
8DZL
,
5C0Z
,
7LJX
,
5C9M
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