Reactome | pSirpa_Rat [plasma membrane]

pSirpa_Rat [plasma membrane]

Stable Identifier

R-RNO-548918

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

External Reference Information

External Reference

UniProt:P97710 Sirpa

Gene Names

Sirpa, Bit, Mfr, Ptpns1, Shps1, Sirp

Chain

signal peptide:1-31, chain:32-509

Reference Genes

BioGPS Gene:25528 Sirpa

ENSEMBL:ENSRNOG00000004763.8 Sirpa

ENSEMBL:ENSRNOG00055006052 Sirpa

ENSEMBL:ENSRNOG00060015357 Sirpa

ENSEMBL:ENSRNOG00065014341 Sirpa

KEGG Gene (Rattus norvegicus):25528 Sirpa

Monarch:25528 Sirpa

NCBI Gene:25528 Sirpa

UCSC:P97710 Sirpa

Reference Transcript

Other Identifiers

10839790

1367881_at

1370574_a_at

17766160

25528

5625701

5654581

5947813

6084995

6379495

6497518

6556276

6557257

6610360

6670946

6726723

AF055065_s_at

A_43_P14890

A_64_P000678

A_64_P000683

D38468_s_at

D85183_s_at

GE1275583

ILMN_1360759

PH_rn_0012083

Participates

as a component of

pSirp alpha:Shp-2 [plasma membrane] (Rattus norvegicus)

as an input of

Recruitment of Shp-2 to pSirp alpha (Rattus norvegicus)

as an output of

Phosphorylation of ITIM in SIRP alpha (Rattus norvegicus)

Other forms of this molecule

Sirpa_Rat [plasma membrane]

phospho-Sirpa [plasma membrane]

Sirpa [ficolin-1-rich granule membrane]

Sirpa [tertiary granule membrane]

Sirpa [plasma membrane]

Modified Residues

Name

O4'-phospho-L-tyrosine at 436

Coordinate

436

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Name

O4'-phospho-L-tyrosine at 460

Coordinate

460

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Name

O4'-phospho-L-tyrosine at 477

Coordinate

477

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Name

O4'-phospho-L-tyrosine at 501

Coordinate

501

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

XP_017446986.1, NP_037148.2

Ensembl

ENSRNOP00000006408, ENSRNOG00000004763, ENSRNOT00000006408

PRO

P97710

RGD

3449

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q06124 PTPN11	4	p-Y542-PTPN11 [cytosol] (R-HSA-1369081) PTPN11 [nucleoplasm] (R-HSA-8937745) PTPN11 [cytosol] (R-HSA-162563) p-Y542,Y580-PTPN11 [cytosol] (R-HSA-162573)	0.564	3
UniProt:P41499 Ptpn11	5	p-Y-Shp2 [cytosol] (R-RNO-1369098) Ptpn11 [cytosol] (R-RNO-548923) PTPN11 [nucleoplasm] (R-RNO-8937745) PTPN11 [cytosol] (R-RNO-162563) phospho-p-Y542,Y580-PTPN11 [cytosol] (R-RNO-162573)	0.544	3
UniProt:Q9R044 Nphs1	4	Nephrin_RAT [plasma membrane] (R-RNO-451392) p-Nephrin_RAT [plasma membrane] (R-RNO-451715) phospho-Nphs1 [plasma membrane] (R-RNO-373636) Nphs1 [plasma membrane] (R-RNO-8981500)	0.524	2

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