Reactome | Ksr2 [cytosol]

Ksr2 [cytosol]

Stable Identifier

R-RNO-5672589

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

KSR2, F1LY04

Locations in the PathwayBrowser

Expand all

Signal Transduction (Rattus norvegicus)

- MAPK family signaling cascades (Rattus norvegicus)
  - MAPK1/MAPK3 signaling (Rattus norvegicus)
    - RAF/MAP kinase cascade (Rattus norvegicus)
      - MAP2K and MAPK activation (Rattus norvegicus)
        
        Dissociation of RAS:RAF complex (Rattus norvegicus)
        
        RAF/MAPK scaffolds [cytosol] (Rattus norvegicus)
        
        Ksr2 [cytosol] (Rattus norvegicus)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Rattus norvegicus)
        
        RAF/MAPK scaffolds [cytosol] (Rattus norvegicus)
        
        Ksr2 [cytosol] (Rattus norvegicus)
        
        Dual mechanism MAP2K inhibitors bind MAP2Ks (Rattus norvegicus)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
        
        RAF/MAPK scaffolds [cytosol] (Rattus norvegicus)
        
        Ksr2 [cytosol] (Rattus norvegicus)
        
        activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Rattus norvegicus)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
        
        RAF/MAPK scaffolds [cytosol] (Rattus norvegicus)
        
        Ksr2 [cytosol] (Rattus norvegicus)
        
        Dual mechanism MAPK inhibitors bind MAPKs (Rattus norvegicus)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
        
        RAF/MAPK scaffolds [cytosol] (Rattus norvegicus)
        
        Ksr2 [cytosol] (Rattus norvegicus)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Rattus norvegicus)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
        
        RAF/MAPK scaffolds [cytosol] (Rattus norvegicus)
        
        Ksr2 [cytosol] (Rattus norvegicus)
        
        MAP2Ks and MAPKs bind to the activated RAF complex (Rattus norvegicus)
        
        RAF/MAPK scaffolds [cytosol] (Rattus norvegicus)
        
        Ksr2 [cytosol] (Rattus norvegicus)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
        
        RAF/MAPK scaffolds [cytosol] (Rattus norvegicus)
        
        Ksr2 [cytosol] (Rattus norvegicus)
        
        MAP2Ks phosphorylate MAPKs (Rattus norvegicus)
        
        activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Rattus norvegicus)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
        
        RAF/MAPK scaffolds [cytosol] (Rattus norvegicus)
        
        Ksr2 [cytosol] (Rattus norvegicus)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Rattus norvegicus)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
        
        RAF/MAPK scaffolds [cytosol] (Rattus norvegicus)
        
        Ksr2 [cytosol] (Rattus norvegicus)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
        
        RAF/MAPK scaffolds [cytosol] (Rattus norvegicus)
        
        Ksr2 [cytosol] (Rattus norvegicus)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Rattus norvegicus)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
        
        RAF/MAPK scaffolds [cytosol] (Rattus norvegicus)
        
        Ksr2 [cytosol] (Rattus norvegicus)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Rattus norvegicus)
        
        RAF/MAPK scaffolds [cytosol] (Rattus norvegicus)
        
        Ksr2 [cytosol] (Rattus norvegicus)
        
        RAF phosphorylates MAP2K dimer (Rattus norvegicus)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
        
        RAF/MAPK scaffolds [cytosol] (Rattus norvegicus)
        
        Ksr2 [cytosol] (Rattus norvegicus)
        
        activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Rattus norvegicus)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
        
        RAF/MAPK scaffolds [cytosol] (Rattus norvegicus)
        
        Ksr2 [cytosol] (Rattus norvegicus)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
        
        RAF/MAPK scaffolds [cytosol] (Rattus norvegicus)
        
        Ksr2 [cytosol] (Rattus norvegicus)
        
        Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Rattus norvegicus)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Rattus norvegicus)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
        
        RAF/MAPK scaffolds [cytosol] (Rattus norvegicus)
        
        Ksr2 [cytosol] (Rattus norvegicus)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
        
        RAF/MAPK scaffolds [cytosol] (Rattus norvegicus)
        
        Ksr2 [cytosol] (Rattus norvegicus)
        
        Single mechanism MAPK inhibitors bind phosphorylated MAPK (Rattus norvegicus)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Rattus norvegicus)
        
        RAF/MAPK scaffolds [cytosol] (Rattus norvegicus)
        
        Ksr2 [cytosol] (Rattus norvegicus)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Rattus norvegicus)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Rattus norvegicus)
        
        RAF/MAPK scaffolds [cytosol] (Rattus norvegicus)
        
        Ksr2 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:F1LY04

Gene Names

Ksr2

Reference Genes

ENSEMBL:ENSRNOG00000028630

ENSEMBL:ENSRNOG00000028630.7 Ksr2

Other Identifiers

10762474

17678433

288691

5628797

5673641

5716173

5831383

5832922

5882872

5912100

5917888

5948471

5959660

6018324

6032988

6056287

6090390

6145970

6166237

6184494

6236214

6382154

6446553

6481201

6597323

6621016

6721739

A_44_P119060

A_64_P085013

GO:0003824

GO:0004672

GO:0004674

GO:0005078

GO:0005524

GO:0005829

GO:0005886

GO:0006468

GO:0016740

GO:0019722

GO:0023052

GO:0031434

GO:0036211

GO:0043410

GO:0060090

GO:0120162

GO:0140096

ILMN_1370096

PH_rn_0015249

Participates

as a candidate of

RAF/MAPK scaffolds [cytosol] (Rattus norvegicus)

Inferred From

KSR2 [cytosol] (Homo sapiens)

Cross References

Ensembl

ENSRNOT00000046190, ENSRNOG00000028630, ENSRNOP00000041584

RGD

1562674

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