Reactome | Rad51ap1 [nucleoplasm]

Rad51ap1 [nucleoplasm]

Stable Identifier

R-RNO-5685301

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

RAD51AP1, A0A8I6GE54

Locations in the PathwayBrowser

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DNA Repair (Rattus norvegicus)

- DNA Double-Strand Break Repair (Rattus norvegicus)
  - Homology Directed Repair (Rattus norvegicus)
    - HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Rattus norvegicus)
      - HDR through Homologous Recombination (HRR) (Rattus norvegicus)
        
        D-loop extension by DNA polymerases (Rattus norvegicus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Rattus norvegicus)
        
        BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Rattus norvegicus)
        
        Rad51ap1 [nucleoplasm] (Rattus norvegicus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Rattus norvegicus)
        
        BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Rattus norvegicus)
        
        Rad51ap1 [nucleoplasm] (Rattus norvegicus)
        
        Homologous DNA Pairing and Strand Exchange (Rattus norvegicus)
        
        CX3 complex binds D-loop structures (Rattus norvegicus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Rattus norvegicus)
        
        BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Rattus norvegicus)
        
        Rad51ap1 [nucleoplasm] (Rattus norvegicus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Rattus norvegicus)
        
        BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Rattus norvegicus)
        
        Rad51ap1 [nucleoplasm] (Rattus norvegicus)
        
        D-loop formation mediated by PALB2, BRCA2 and RAD51 (Rattus norvegicus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Rattus norvegicus)
        
        BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Rattus norvegicus)
        
        Rad51ap1 [nucleoplasm] (Rattus norvegicus)
        
        Rad51ap1 [nucleoplasm] (Rattus norvegicus)
        
        Resolution of D-Loop Structures (Rattus norvegicus)
        
        Resolution of D-loop Structures through Holliday Junction Intermediates (Rattus norvegicus)
        
        Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Rattus norvegicus)
        
        Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Rattus norvegicus)
        
        BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Rattus norvegicus)
        
        Rad51ap1 [nucleoplasm] (Rattus norvegicus)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Rattus norvegicus)
        
        BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Rattus norvegicus)
        
        Rad51ap1 [nucleoplasm] (Rattus norvegicus)
        
        Ligation of DNA and formation of Holliday structures following repair synthesis (Rattus norvegicus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Rattus norvegicus)
        
        BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Rattus norvegicus)
        
        Rad51ap1 [nucleoplasm] (Rattus norvegicus)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Rattus norvegicus)
        
        BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Rattus norvegicus)
        
        Rad51ap1 [nucleoplasm] (Rattus norvegicus)
        
        MUS81:EME1,EME2 cleaves D-loop (Rattus norvegicus)
        
        Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Rattus norvegicus)
        
        BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Rattus norvegicus)
        
        Rad51ap1 [nucleoplasm] (Rattus norvegicus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Rattus norvegicus)
        
        BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Rattus norvegicus)
        
        Rad51ap1 [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:A0A8I6GE54

Gene Names

Rad51ap1

Reference Genes

ENSEMBL:ENSRNOG00000059878

ENSEMBL:ENSRNOG00000059878.2 Rad51ap1

Other Identifiers

1380277_at

17795097

5637889

5779161

5871541

5980397

6171503

6219454

6374746

6386855

6564082

6663276

689055

A_44_P623426

A_64_P084619

GE1205570

GO:0000217

GO:0000724

GO:0000785

GO:0003677

GO:0003690

GO:0003697

GO:0003723

GO:0005634

GO:0005694

GO:0006281

GO:0006310

GO:0006974

GO:0010569

GO:0010845

GO:0022414

GO:0032991

GO:0036297

GO:0043226

GO:0062037

GO:0071479

GO:0140013

GO:1905168

PH_rn_0009311

rc_AI639142_at

Participates

as an input of

D-loop formation mediated by PALB2, BRCA2 and RAD51 (Rattus norvegicus)

as a component of

BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Rattus norvegicus)

Inferred From

RAD51AP1 [nucleoplasm] (Homo sapiens)

Cross References

Ensembl

ENSRNOT00000119755, ENSRNOP00000085679, ENSRNOG00000059878

RGD

1597431

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