Reactome | Itgb1 [plasma membrane]

Itgb1 [plasma membrane]

Stable Identifier

R-RNO-57596

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

ITGB1, P49134

Locations in the PathwayBrowser

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Signal Transduction (Rattus norvegicus)

- Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
  - Signaling by MET (Rattus norvegicus)
    - MET promotes cell motility (Rattus norvegicus)
      - MET activates PTK2 signaling (Rattus norvegicus)
        
        PTK2 binds activated MET (Rattus norvegicus)
        
        Integrin alpha2beta1,alpha3:beta1:(collagen,laminin,fibronectin) [plasma membrane] (Rattus norvegicus)
        
        Integrin alpha2beta1,alpha3beta1 [plasma membrane] (Rattus norvegicus)
        
        Integrin alpha2beta1 [plasma membrane] (Rattus norvegicus)
        
        Itgb1 [plasma membrane] (Rattus norvegicus)
        
        Integrin alpha3beta1 [plasma membrane] (Rattus norvegicus)
        
        Itgb1 [plasma membrane] (Rattus norvegicus)
      - MET interacts with TNS proteins (Rattus norvegicus)
        
        MET binds TNS4 (Rattus norvegicus)
        
        HGF:p-4Y-MET dimer:TNS4:ITGB1 [plasma membrane] (Rattus norvegicus)
        
        TNS4:ITGB1 [plasma membrane] (Rattus norvegicus)
        
        Itgb1 [plasma membrane] (Rattus norvegicus)
        
        TNS4:ITGB1 [plasma membrane] (Rattus norvegicus)
        
        Itgb1 [plasma membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P49134 Itgb1

Gene Names

Itgb1

Chain

signal peptide:1-20, chain:21-798

Reference Genes

BioGPS Gene:24511 Itgb1

KEGG Gene (Rattus norvegicus):24511 Itgb1

Monarch:24511 Itgb1

NCBI Gene:24511 Itgb1

UCSC:P49134 Itgb1

Reference Transcript

RefSeq:NM_017022.2 Itgb1

Participant Of

hasComponent

input

ILK interacts with beta-1 integrin

Other forms of this molecule

Itgb1 [plasma membrane]

Inferred From

ITGB1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_058718.2

Target Pathogen

5b354852be737e166372eba8

PRO

P49134

RGD

2927

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