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Stx1a [plasma membrane]
Stable Identifier
R-RNO-6794247
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
plasma membrane
Synonyms
Syntaxin-1A, STX1A_RAT
Locations in the PathwayBrowser
Expand all
Developmental Biology (Rattus norvegicus)
LGI-ADAM interactions (Rattus norvegicus)
LGI3 binds ADAM22,23,synatxin1 (Rattus norvegicus)
ADAM22,23,syntaxin1 [plasma membrane] (Rattus norvegicus)
STX1 [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
LGI3;ADAM22,23,synatxin1 [plasma membrane] (Rattus norvegicus)
ADAM22,23,syntaxin1 [plasma membrane] (Rattus norvegicus)
STX1 [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
Immune System (Rattus norvegicus)
Cytokine Signaling in Immune system (Rattus norvegicus)
Signaling by Interleukins (Rattus norvegicus)
Other interleukin signaling (Rattus norvegicus)
TXLNA (IL14) binds syntaxin1A (Rattus norvegicus)
STXA1:SNAP25,STXBP2, VAMP2 [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
TXLNA:STX1A [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
Neuronal System (Rattus norvegicus)
Transmission across Chemical Synapses (Rattus norvegicus)
Neurotransmitter release cycle (Rattus norvegicus)
Acetylcholine Neurotransmitter Release Cycle (Rattus norvegicus)
Acetylcholine synaptic vesicle docking and priming (Rattus norvegicus)
Docked acetylcholine loaded Synaptic Vesicle [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
Release of acetylcholine at the synapse (Rattus norvegicus)
Docked acetylcholine loaded Synaptic Vesicle [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
SNARE complex [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
Dopamine Neurotransmitter Release Cycle (Rattus norvegicus)
Dopamine synaptic vesicle docking and priming (Rattus norvegicus)
Docked dopamine loaded synaptic vesicle [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
Release of docked dopamine loaded synaptic vesicle (Rattus norvegicus)
Docked dopamine loaded synaptic vesicle [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
SNARE complex [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
GABA synthesis, release, reuptake and degradation (Rattus norvegicus)
GABA loaded synaptic vesicle Docking and Priming (Rattus norvegicus)
Docked GABA loaded synaptic vesicle [cytosol] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
Release of GABA at the synapse (Rattus norvegicus)
Docked GABA loaded synaptic vesicle [cytosol] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
SNARE complex:Ca2+ [plasma membrane] (Rattus norvegicus)
SNARE complex [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
Glutamate Neurotransmitter Release Cycle (Rattus norvegicus)
Glutamate synaptic vesicle docking and priming (Rattus norvegicus)
Docked Glutamate Loaded Synaptic Vesicle [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
Release of L-Glutamate at the synapse (Rattus norvegicus)
Docked Glutamate Loaded Synaptic Vesicle [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
SNARE complex:Ca2+ [plasma membrane] (Rattus norvegicus)
SNARE complex [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
Norepinephrine Neurotransmitter Release Cycle (Rattus norvegicus)
Noradrenalin synaptic vesicle docking and priming (Rattus norvegicus)
Docked Noradrenalin loaded synaptic vesicle [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
Release of noradrenaline at the synapse (Rattus norvegicus)
Docked Noradrenalin loaded synaptic vesicle [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
SNARE complex [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
Serotonin Neurotransmitter Release Cycle (Rattus norvegicus)
Release of docked serotonin loaded synaptic vesicle (Rattus norvegicus)
Docked serotonin loaded synaptic vesicle [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
SNARE complex [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
Serotonin loaded synaptic vesicle docking and priming (Rattus norvegicus)
Docked serotonin loaded synaptic vesicle [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
Stx1a [plasma membrane] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P32851 Stx1a
Gene Names
Stx1a, Sap
Chain
chain:1-288
Reference Genes
BioGPS Gene:116470 Stx1a
ENSEMBL:ENSRNOG00000029165 Stx1a
KEGG Gene (Rattus norvegicus):116470 Stx1a
Monarch:116470 Stx1a
NCBI Gene:116470 Stx1a
UCSC:P32851 Stx1a
Reference Transcript
RefSeq:NM_053788.2 Stx1a
Other Identifiers
10761227
10763171
116470
1387359_at
1387360_at
17677059
17679252
5650293
5782938
5792768
5900870
5989906
6120230
6196243
6259715
6290081
6392895
6523065
6666607
A_64_P025381
D10392_i_at
D12519_s_at
GE1133741
GO:0000149
GO:0001669
GO:0001956
GO:0003674
GO:0005484
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005635
GO:0005737
GO:0005856
GO:0005886
GO:0005887
GO:0006464
GO:0006810
GO:0006836
GO:0006886
GO:0006887
GO:0006906
GO:0007165
GO:0007267
GO:0008021
GO:0008076
GO:0008092
GO:0008150
GO:0009629
GO:0010701
GO:0010807
GO:0012505
GO:0014069
GO:0015031
GO:0016020
GO:0016021
GO:0016079
GO:0016081
GO:0016192
GO:0016925
GO:0017022
GO:0017156
GO:0017157
GO:0019855
GO:0019869
GO:0019899
GO:0019900
GO:0019904
GO:0022607
GO:0030054
GO:0030073
GO:0030141
GO:0030285
GO:0030424
GO:0030672
GO:0030674
GO:0031201
GO:0031410
GO:0031629
GO:0031965
GO:0032028
GO:0032940
GO:0032991
GO:0033605
GO:0035493
GO:0042641
GO:0042734
GO:0042802
GO:0043005
GO:0043008
GO:0043226
GO:0043229
GO:0044325
GO:0044877
GO:0045055
GO:0045202
GO:0045921
GO:0045956
GO:0046879
GO:0047485
GO:0048278
GO:0048306
GO:0048488
GO:0048787
GO:0050877
GO:0061024
GO:0061025
GO:0065003
GO:0070032
GO:0070033
GO:0070044
GO:0072657
GO:0098815
GO:0098978
GO:0099056
GO:2000463
ILMN_1350669
PH_rn_0002084
Participant Of
hasMember
STX1 [plasma membrane]
hasComponent
Docked acetylcholine loaded Synaptic Vesicle [plasma membrane]
Docked dopamine loaded synaptic vesicle [plasma membrane]
Docked GABA loaded synaptic vesicle [cytosol]
Docked Glutamate Loaded Synaptic Vesicle [plasma membrane]
Docked Noradrenalin loaded synaptic vesicle [plasma membrane]
Docked serotonin loaded synaptic vesicle [plasma membrane]
SNARE complex [plasma membrane]
Stx1a:Munc18:Mint1,2 [plasma membrane]
STXA1:SNAP25,STXBP2, VAMP2 [plasma membrane]
TXLNA:STX1A [plasma membrane]
input
Acetylcholine synaptic vesicle docking and priming
Dopamine synaptic vesicle docking and priming
GABA loaded synaptic vesicle Docking and Priming
Glutamate synaptic vesicle docking and priming
Noradrenalin synaptic vesicle docking and priming
Serotonin loaded synaptic vesicle docking and priming
TXLNA (IL14) binds syntaxin1A
Other forms of this molecule
Stx1a [cytosol]
Inferred From
STX1A [plasma membrane] (Homo sapiens)
Cross References
RefSeq
NP_446240.2
Ensembl
ENSRNOG00000029165
,
ENSRNOP00000040699
,
ENSRNOT00000049601
PRO
P32851
RGD
69430
PDB
1JTH
,
1BR0
,
1URQ
,
2M8R
,
1KIL
,
1EZ3
,
1HVV
,
5CCG
,
3RL0
,
3J96
,
5KJ7
,
2N1T
,
4JEU
,
1SFC
,
5KJ8
,
3RK3
,
6IP1
,
4JEH
,
6MDN
,
3J99
,
6MDM
,
3RK2
,
3J98
,
1N7S
,
3C98
,
3J97
,
5CCH
,
5W5C
,
3IPD
,
6MTI
,
3HD7
,
5CCI
,
2BU0
,
5W5D
Interactors (13)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P60881
3
Snap25 [tertiary granule membrane]
(R-RNO-6806142)
Snap25 [plasma membrane]
(R-RNO-2029017)
Snap25 [specific granule membrane]
(R-RNO-6806154)
0.965
30
UniProt:P61765 Stxbp1
1
Stxbp1 [cytosol]
(R-RNO-6794254)
0.921
22
UniProt:P60879 Snap25
0.793
7
UniProt:P60881-2 SNAP25
0.756
6
UniProt:P63045
10
Vamp2 [plasma membrane]
(R-RNO-210516)
Vamp2 [clathrin-sculpted monoamine transport vesicle membrane]
(R-RNO-379363)
Vamp2 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]
(R-RNO-917738)
Vamp2 [clathrin-sculpted glutamate transport vesicle membrane]
(R-RNO-372517)
Vamp2 [cytosol]
(R-RNO-9609882)
Vamp2 [lysosomal membrane]
(R-RNO-432703)
Vamp2 [Golgi membrane]
(R-RNO-375425)
Vamp2 [cytoplasmic vesicle membrane]
(R-RNO-375436)
Vamp2 [secretory granule membrane]
(R-RNO-376363)
Vamp2 [clathrin-coated endocytic vesicle membrane]
(R-RNO-8869129)
0.752
9
UniProt:P60880-2 SNAP25
0.743
4
UniProt:O35430 Apba1
2
Apba1 [cytosol]
(R-RNO-5336459)
Apba1 [cytosol]
(R-RNO-6794228)
0.656
3
UniProt:O14810 CPLX1
1
CPLX1 [cytosol]
(R-HSA-210385)
0.656
3
UniProt:Q63666 VAMP1
0.613
3
UniProt:P63041
1
Cplx1 [cytosol]
(R-RNO-210385)
0.564
2
UniProt:Q5SQN1 SNP47
0.556
3
UniProt:Q62717 CAPS1
0.499
3
UniProt:P18708 NSF
0.488
4
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