Spar binds Psd-95

Stable Identifier
R-RNO-6794335
Type
Reaction [binding]
Species
Rattus norvegicus
Compartment
General
SVG |   | PPTX  | SBGN
Spar binds Psd-95

Spine-Associated RapGAP (SPAR) is a postsynaptic Rap-specific GTPase-activating protein (RapGAP) that reorganizes actin cytoskeleton and drives dentritic spine head growth. SPAR interacts with the guanylate kinase-like (GK) domain of Disks large homolog proteins (DSGs) forming a complex with NMDA receptors in brain (Pak et al. 2001).

Literature References
PubMed ID Title Journal Year
11502259 Regulation of dendritic spine morphology by SPAR, a PSD-95-associated RapGAP

Pak, DT, Yang, S, Rudolph-Correia, S, Kim, E, Sheng, M

Neuron 2001
Participants
Orthologous Events
Authored
Reviewed
Created
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